TY - JOUR

T1 - Limits of Solid Solutions and Thermal Deformations in the L-Alanine–L-Serine Amino Acid System

AU - Kotelnikova, Elena

AU - Sadovnichii , Roman

AU - Kryuchkova , Lyudmila

AU - Lorenz, Heike

N1 - Kotelnikova, E.; Sadovnichii, R.; Kryuchkova, L.; Lorenz, H. Limits of Solid Solutions and Thermal Deformations in the L-Alanine–L-Serine Amino Acid System. Crystals 2020, 10, 618.

PY - 2020/7/16

Y1 - 2020/7/16

N2 - The limits of solid solutions and thermal deformations in the L-alanine–L-serine (L-ala–L-ser) amino acid system have been determined. Thirteen amino acid mixtures with various proportions of the components L-ser/L-ala were studied using powder X-ray diffraction techniques. It was found that the regions of solid solutions in the system are rather limited and cover less than 10 mol. % from each component side. The thermal behavior of the components L-ser and L-ala and the composition L-ser/L-ala = 90/10 were studied by temperature-resolved powder X-ray diffraction. The heating of L-ser and L-ala only causes thermal deformations, while two-phase mixtures with the 90/10 L-ser/L-ala ratio form solid solutions at elevated temperatures. Additionally, the parameters of the thermal deformation tensor for L-ser and L-ala were calculated, and the figures of their thermal expansion coefficients were plotted and analyzed. The study conducted is of high applicability, since amino acids are active components of various biological, geological, and technological processes, including those at elevated temperatures, and have numerous applications in life-science industries.

AB - The limits of solid solutions and thermal deformations in the L-alanine–L-serine (L-ala–L-ser) amino acid system have been determined. Thirteen amino acid mixtures with various proportions of the components L-ser/L-ala were studied using powder X-ray diffraction techniques. It was found that the regions of solid solutions in the system are rather limited and cover less than 10 mol. % from each component side. The thermal behavior of the components L-ser and L-ala and the composition L-ser/L-ala = 90/10 were studied by temperature-resolved powder X-ray diffraction. The heating of L-ser and L-ala only causes thermal deformations, while two-phase mixtures with the 90/10 L-ser/L-ala ratio form solid solutions at elevated temperatures. Additionally, the parameters of the thermal deformation tensor for L-ser and L-ala were calculated, and the figures of their thermal expansion coefficients were plotted and analyzed. The study conducted is of high applicability, since amino acids are active components of various biological, geological, and technological processes, including those at elevated temperatures, and have numerous applications in life-science industries.

KW - CRYSTALLINE 1/1 COMPLEXES

KW - DL-SERINE

KW - EXPANSION

KW - L-alanine

KW - L-serine

KW - MOLECULAR AGGREGATION

KW - PRESSURE

KW - PXRD

KW - SINGLE-CRYSTAL

KW - SOLUBILITY

KW - TRPXRD

KW - enantiomers

KW - isomorphic miscibility

KW - thermal expansion

UR - https://www.mendeley.com/catalogue/fe184193-0b0d-3ca9-bc69-364defb3df55/

U2 - 10.3390/cryst10070618

DO - 10.3390/cryst10070618

M3 - Article

VL - 10

JO - Crystals

JF - Crystals

SN - 2073-4352

IS - 7

M1 - 618

ER -