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Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation. / Видякина, Александра Александровна; Силонов, Сергей Александрович; Говди, Анастасия Иосифовна; Иванов, Александр Юльевич; Подольская, Екатерина Петровна; Балова, Ирина Анатольевна; Bräse, Stefan; Данилкина, Наталья Александровна.

в: Organic and Biomolecular Chemistry, Том 22, № 37, 03.07.2024, стр. 7637-7642.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Видякина, АА, Силонов, СА, Говди, АИ, Иванов, АЮ, Подольская, ЕП, Балова, ИА, Bräse, S & Данилкина, НА 2024, 'Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation', Organic and Biomolecular Chemistry, Том. 22, № 37, стр. 7637-7642. https://doi.org/10.1039/D4OB01032A

APA

Видякина, А. А., Силонов, С. А., Говди, А. И., Иванов, А. Ю., Подольская, Е. П., Балова, И. А., Bräse, S., & Данилкина, Н. А. (2024). Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation. Organic and Biomolecular Chemistry, 22(37), 7637-7642. https://doi.org/10.1039/D4OB01032A

Vancouver

Видякина АА, Силонов СА, Говди АИ, Иванов АЮ, Подольская ЕП, Балова ИА и пр. Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation. Organic and Biomolecular Chemistry. 2024 Июль 3;22(37):7637-7642. https://doi.org/10.1039/D4OB01032A

Author

Видякина, Александра Александровна ; Силонов, Сергей Александрович ; Говди, Анастасия Иосифовна ; Иванов, Александр Юльевич ; Подольская, Екатерина Петровна ; Балова, Ирина Анатольевна ; Bräse, Stefan ; Данилкина, Наталья Александровна. / Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation. в: Organic and Biomolecular Chemistry. 2024 ; Том 22, № 37. стр. 7637-7642.

BibTeX

@article{53c3f5e5fb984799b3d6b1d62c86b55e,
title = "Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation",
abstract = "Conjugates of benzothiophene-fused azacyclononyne BT9N-NH2 with fluorescent dyes were developed to visualise azidoglycans intracellularly. The significance of the cycloalkyne core was demonstrated by comparing new reagents with DBCO- and BCN-dye conjugates. To reduce non-specificity during intracellular bioconjugation using SPAAC, less reactive BT9N-dye reagents are preferred over highly reactive DBCO- and BCN-dye conjugates.",
author = "Видякина, {Александра Александровна} and Силонов, {Сергей Александрович} and Говди, {Анастасия Иосифовна} and Иванов, {Александр Юльевич} and Подольская, {Екатерина Петровна} and Балова, {Ирина Анатольевна} and Stefan Br{\"a}se and Данилкина, {Наталья Александровна}",
year = "2024",
month = jul,
day = "3",
doi = "10.1039/D4OB01032A",
language = "English",
volume = "22",
pages = "7637--7642",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
number = "37",

}

RIS

TY - JOUR

T1 - Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation

AU - Видякина, Александра Александровна

AU - Силонов, Сергей Александрович

AU - Говди, Анастасия Иосифовна

AU - Иванов, Александр Юльевич

AU - Подольская, Екатерина Петровна

AU - Балова, Ирина Анатольевна

AU - Bräse, Stefan

AU - Данилкина, Наталья Александровна

PY - 2024/7/3

Y1 - 2024/7/3

N2 - Conjugates of benzothiophene-fused azacyclononyne BT9N-NH2 with fluorescent dyes were developed to visualise azidoglycans intracellularly. The significance of the cycloalkyne core was demonstrated by comparing new reagents with DBCO- and BCN-dye conjugates. To reduce non-specificity during intracellular bioconjugation using SPAAC, less reactive BT9N-dye reagents are preferred over highly reactive DBCO- and BCN-dye conjugates.

AB - Conjugates of benzothiophene-fused azacyclononyne BT9N-NH2 with fluorescent dyes were developed to visualise azidoglycans intracellularly. The significance of the cycloalkyne core was demonstrated by comparing new reagents with DBCO- and BCN-dye conjugates. To reduce non-specificity during intracellular bioconjugation using SPAAC, less reactive BT9N-dye reagents are preferred over highly reactive DBCO- and BCN-dye conjugates.

U2 - 10.1039/D4OB01032A

DO - 10.1039/D4OB01032A

M3 - Article

VL - 22

SP - 7637

EP - 7642

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 37

ER -

ID: 125928744