The paper we summarizes and discusses experience of medical statistics data processing and mapping, gained in 2019-2020 in the frames of study devoted to the tuberculosis infection mapping. Basing on this experience, we have formalised a set of research issues, which were elaborated and clarified at the previous stages but demand additional investigations.Additionally, the paper summarises results of design and prototyping of a Web mapping interface implemented as a part of developed medical Geographic Information System (GIS). Developed GIS is aimed onto mapping and analysis of tuberculosis infection data. The overall structure of elaborated GIS is covered also with respect to the detected research issues.