TY - JOUR

T1 - Iridoid glycosides of the tribe Antirrhineae

AU - Sokornova, Sophie V.

AU - Matveeva, Tatiana V.

N1 - Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer Nature B.V.

PY - 2021/8/30

Y1 - 2021/8/30

N2 - The tribe Antirrhineae of Plantaginaceae family is well known for various garden ornamentals (Antirrhinum L., Linaria Mill., Cymbalaria Hill.), numerous medicinal plants (Anarrhinum orientale Benth., Nanorrhinum ramosissimum (Wall.) Betsche, Linaria japonica Miq. etc.), besides, the Linaria genus is famous for the fact that it contains naturally-transgenic plants. Medicinal properties are caused by the presence of a certain spectrum of specialized metabolites. A major role among them in tribe Antirrhineae is played by iridoid glycosides, in particular antirrhinoside, antirrhide, linarioside and 6-O-acetylantirrinoside. This review summarizes the literature data on biosynthesis, methods of analysis, the diversity and distribution of these compounds in the representatives of the tribe, that makes it possible to use the obtained data for chemotaxonomy and pharmacology, and also indicates gaps in our knowledge regarding the biochemistry of such taxonomic groups as Anarrhinum, Maurandya, Gambelia, Chaenorhinum, Antirrhinum and Linaria. The general picture of the state of research indicates directions for future work. Despite the different degrees of study of the tribe representatives, we can conclude the presence of antirrhinoside as a marker of this group of plants.

AB - The tribe Antirrhineae of Plantaginaceae family is well known for various garden ornamentals (Antirrhinum L., Linaria Mill., Cymbalaria Hill.), numerous medicinal plants (Anarrhinum orientale Benth., Nanorrhinum ramosissimum (Wall.) Betsche, Linaria japonica Miq. etc.), besides, the Linaria genus is famous for the fact that it contains naturally-transgenic plants. Medicinal properties are caused by the presence of a certain spectrum of specialized metabolites. A major role among them in tribe Antirrhineae is played by iridoid glycosides, in particular antirrhinoside, antirrhide, linarioside and 6-O-acetylantirrinoside. This review summarizes the literature data on biosynthesis, methods of analysis, the diversity and distribution of these compounds in the representatives of the tribe, that makes it possible to use the obtained data for chemotaxonomy and pharmacology, and also indicates gaps in our knowledge regarding the biochemistry of such taxonomic groups as Anarrhinum, Maurandya, Gambelia, Chaenorhinum, Antirrhinum and Linaria. The general picture of the state of research indicates directions for future work. Despite the different degrees of study of the tribe representatives, we can conclude the presence of antirrhinoside as a marker of this group of plants.

KW - Antirrhineae

KW - Biological/pharmacological activity

KW - Iridoid glycosides

KW - Specialized metabolites

KW - OXIDATIVE STRESS

KW - L. MILL.

KW - Biological

KW - IDENTIFICATION

KW - LINARIA

KW - pharmacological activity

KW - KICKXIA

KW - CHEMICAL-CONSTITUENTS

KW - PICRORHIZA-KURROA

KW - GLUCOSIDES

KW - SPERMINE ALKALOIDS

KW - BIOLOGICAL-CONTROL

UR - http://www.scopus.com/inward/record.url?scp=85113870382&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/f9e2e51b-9923-3563-8e9b-dc0c431c9cdc/

U2 - 10.1007/s11101-021-09774-0

DO - 10.1007/s11101-021-09774-0

M3 - Review article

AN - SCOPUS:85113870382

JO - Phytochemistry Reviews

JF - Phytochemistry Reviews

SN - 1568-7767

ER -