Standard

In-vivo pharmacology of Trace-Amine Associated Receptor 1. / Lam, Vincent M; Espinoza, Stefano; Gerasimov, Andrey S; Gainetdinov, Raul R; Salahpour, Ali.

в: European Journal of Pharmacology, Том 763, № Pt B, 2015, стр. 136-42.

Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование

Harvard

Lam, VM, Espinoza, S, Gerasimov, AS, Gainetdinov, RR & Salahpour, A 2015, 'In-vivo pharmacology of Trace-Amine Associated Receptor 1', European Journal of Pharmacology, Том. 763, № Pt B, стр. 136-42. https://doi.org/10.1016/j.ejphar.2015.06.026

APA

Lam, V. M., Espinoza, S., Gerasimov, A. S., Gainetdinov, R. R., & Salahpour, A. (2015). In-vivo pharmacology of Trace-Amine Associated Receptor 1. European Journal of Pharmacology, 763(Pt B), 136-42. https://doi.org/10.1016/j.ejphar.2015.06.026

Vancouver

Lam VM, Espinoza S, Gerasimov AS, Gainetdinov RR, Salahpour A. In-vivo pharmacology of Trace-Amine Associated Receptor 1. European Journal of Pharmacology. 2015;763(Pt B):136-42. https://doi.org/10.1016/j.ejphar.2015.06.026

Author

Lam, Vincent M ; Espinoza, Stefano ; Gerasimov, Andrey S ; Gainetdinov, Raul R ; Salahpour, Ali. / In-vivo pharmacology of Trace-Amine Associated Receptor 1. в: European Journal of Pharmacology. 2015 ; Том 763, № Pt B. стр. 136-42.

BibTeX

@article{9a47cc3d50564cae8490d151375e84a3,
title = "In-vivo pharmacology of Trace-Amine Associated Receptor 1",
abstract = "Trace-amines (TAs) are endogenous amines that are implicated in several physiological processes including modulation of aminergic neurotransmission. These compounds exert their effect by activating a class of G protein-coupled receptors termed Trace-Amine Associated Receptors (TAARs), where TAAR1 is the only human receptor that has been shown to bind endogenous TAs. Most of the studies have focused on studying the role of TAAR1 on modulation of the dopamine transmission. These studies indicate that TAAR1 is a negative regulator of dopamine transmission making TAAR1 a novel target for neuropsychiatric disorders that arises from dopamine dysfunction such as schizophrenia. This review discusses the unique pharmacology of TAAR1 with the major focus on the physiological role of TAAR1 and its modulation of dopamine transmission.",
keywords = "Amines, Animals, Dopamine, Humans, Ligands, Pharmacological Phenomena, Receptors, G-Protein-Coupled, Signal Transduction, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Lam, {Vincent M} and Stefano Espinoza and Gerasimov, {Andrey S} and Gainetdinov, {Raul R} and Ali Salahpour",
note = "Copyright {\textcopyright} 2015 Elsevier B.V. All rights reserved.",
year = "2015",
doi = "10.1016/j.ejphar.2015.06.026",
language = "English",
volume = "763",
pages = "136--42",
journal = "European Journal of Pharmacology",
issn = "0014-2999",
publisher = "Elsevier",
number = "Pt B",

}

RIS

TY - JOUR

T1 - In-vivo pharmacology of Trace-Amine Associated Receptor 1

AU - Lam, Vincent M

AU - Espinoza, Stefano

AU - Gerasimov, Andrey S

AU - Gainetdinov, Raul R

AU - Salahpour, Ali

N1 - Copyright © 2015 Elsevier B.V. All rights reserved.

PY - 2015

Y1 - 2015

N2 - Trace-amines (TAs) are endogenous amines that are implicated in several physiological processes including modulation of aminergic neurotransmission. These compounds exert their effect by activating a class of G protein-coupled receptors termed Trace-Amine Associated Receptors (TAARs), where TAAR1 is the only human receptor that has been shown to bind endogenous TAs. Most of the studies have focused on studying the role of TAAR1 on modulation of the dopamine transmission. These studies indicate that TAAR1 is a negative regulator of dopamine transmission making TAAR1 a novel target for neuropsychiatric disorders that arises from dopamine dysfunction such as schizophrenia. This review discusses the unique pharmacology of TAAR1 with the major focus on the physiological role of TAAR1 and its modulation of dopamine transmission.

AB - Trace-amines (TAs) are endogenous amines that are implicated in several physiological processes including modulation of aminergic neurotransmission. These compounds exert their effect by activating a class of G protein-coupled receptors termed Trace-Amine Associated Receptors (TAARs), where TAAR1 is the only human receptor that has been shown to bind endogenous TAs. Most of the studies have focused on studying the role of TAAR1 on modulation of the dopamine transmission. These studies indicate that TAAR1 is a negative regulator of dopamine transmission making TAAR1 a novel target for neuropsychiatric disorders that arises from dopamine dysfunction such as schizophrenia. This review discusses the unique pharmacology of TAAR1 with the major focus on the physiological role of TAAR1 and its modulation of dopamine transmission.

KW - Amines

KW - Animals

KW - Dopamine

KW - Humans

KW - Ligands

KW - Pharmacological Phenomena

KW - Receptors, G-Protein-Coupled

KW - Signal Transduction

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1016/j.ejphar.2015.06.026

DO - 10.1016/j.ejphar.2015.06.026

M3 - Review article

C2 - 26093041

VL - 763

SP - 136

EP - 142

JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

SN - 0014-2999

IS - Pt B

ER -

ID: 5835044