The article discusses the interconnection of women's psychological well-being with their personal characteristics, namely with self-attitude and life-meaning orientations. In the course of the study, reliable differences in the level of the psychological well-being in the different age groups of women were found. Women in the age group of 35 and older have a higher level of psychological well-being on integral scale as well as on scales of tension and sensibility and self-rating of their health. During the research of the self-relation in this age group reliable higher values of self-confidence, self-sequencing and self-guiding were registered, in comparison with the age group of women under 35. The article presents the results of the comparative study of the interconnection of psychological well-being with self-attitude and life-meaning orientations in different age groups of women. Positive relationship of psychological well-being with total positive self-relation, self-respect, self-understanding, life goals, process of life, life result, self-locus control and integral value of the meaningfulness of life was registered in both age groups. Positive relationship of psychological well-being with self-sympathy, self-confidence, self-acceptance, self-interest, life locus control was found in the age group of women under 35.