TY - CHAP

T1 - INTERACTION OF HUMAN SERUM ALBUMIN WITH DIVALENT METAL IONS

AU - Пастон, Софья Владимировна

AU - Федотова, Елизавета Владиславовна

AU - Горох, Антон Дмитриевич

N1 - Conference code: 10

PY - 2023/9/26

Y1 - 2023/9/26

N2 - In this work, the method of FTIR spectroscopy on the ATR crystal with deconvolution of the Amide I band was used to study the secondary structure of the protein. The tertiary structure of HSA was studied by detection of absorptionand intrinsic fluorescence spectra of the protein. The zeta potential method was used to characterize the surface charge of protein particles. In this study, we investigated the HSA in the solution of metal ions Mg2+, Mn2+, Co2+ and Cu2+when the concentration of metal ions was varied in the range of [Co2+]:[HSA] from 0 to 100, [Mg2+]:[HSA] from 0 to 10000, [Mn2+]:[HSA] from 0 to 50, [Cu2+]:[HSA] from 0 to 50.

AB - In this work, the method of FTIR spectroscopy on the ATR crystal with deconvolution of the Amide I band was used to study the secondary structure of the protein. The tertiary structure of HSA was studied by detection of absorptionand intrinsic fluorescence spectra of the protein. The zeta potential method was used to characterize the surface charge of protein particles. In this study, we investigated the HSA in the solution of metal ions Mg2+, Mn2+, Co2+ and Cu2+when the concentration of metal ions was varied in the range of [Co2+]:[HSA] from 0 to 100, [Mg2+]:[HSA] from 0 to 10000, [Mn2+]:[HSA] from 0 to 50, [Cu2+]:[HSA] from 0 to 50.

U2 - 10.25205/978-5-4437-1526-1-156

DO - 10.25205/978-5-4437-1526-1-156

M3 - Conference abstracts

SP - 293

EP - 294

BT - X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023: Cб. тез. / АНО «Инновационный центр Кольцово». — Новосибирск : ИПЦ НГУ, 2023. — 814 с.

PB - АНО «Инновационный центр Кольцово»

CY - Новосибирск

Y2 - 26 September 2023 through 29 September 2023

ER -