Результаты исследований: Научные публикации в периодических изданиях › статья в журнале по материалам конференции
Interaction of HMGB-domain proteins from differentiated cells with DNA modified by cisplatin. / Chikhirzhina, E. V. ; Starkova, T. Yu. ; Polyanichko, A. M. .
в: Journal of Physics: Conference Series, Том 1697, № 1, 012046, 17.12.2020.Результаты исследований: Научные публикации в периодических изданиях › статья в журнале по материалам конференции
}
TY - JOUR
T1 - Interaction of HMGB-domain proteins from differentiated cells with DNA modified by cisplatin
AU - Chikhirzhina, E. V.
AU - Starkova, T. Yu.
AU - Polyanichko, A. M.
PY - 2020/12/17
Y1 - 2020/12/17
N2 - Using UV absorption spectroscopy and circular dichroism, we studied the interaction of DNA-cisplatin complexes with nonhistone chromosomal proteins HMGB1 and HMGB2. It was shown that the presence of platinum ions affected the ability of HMGB2 to form large supramolecular complexes with DNA. The role of C-terminal domain of the HMGB1/2 proteins is discussed.
AB - Using UV absorption spectroscopy and circular dichroism, we studied the interaction of DNA-cisplatin complexes with nonhistone chromosomal proteins HMGB1 and HMGB2. It was shown that the presence of platinum ions affected the ability of HMGB2 to form large supramolecular complexes with DNA. The role of C-terminal domain of the HMGB1/2 proteins is discussed.
UR - http://www.scopus.com/inward/record.url?scp=85098320281&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/b4571018-93da-31bc-b32e-e59939bf5045/
U2 - 10.1088/1742-6596/1697/1/012046
DO - 10.1088/1742-6596/1697/1/012046
M3 - Conference article
VL - 1697
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012046
T2 - International Conference PhysicA.SPb 2020
Y2 - 19 October 2020 through 23 October 2020
ER -
ID: 72132017