Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands

Standard

Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands. / Kas'yanenko, N. A.; Nikolenko, O. V.; Prokhorova, S. A.; D'yachenko, S. A.; Smorygo, N. A.; Ivin, B. A.; Frisman, E. V.

в: Molecular Biology, Том 31, № 2, 03.1997, стр. 240-244.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Kas'yanenko, NA, Nikolenko, OV, Prokhorova, SA, D'yachenko, SA, Smorygo, NA, Ivin, BA & Frisman, EV 1997, 'Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands', Molecular Biology, Том. 31, № 2, стр. 240-244.

APA

Kas'yanenko, N. A., Nikolenko, O. V., Prokhorova, S. A., D'yachenko, S. A., Smorygo, N. A., Ivin, B. A., & Frisman, E. V. (1997). Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands. Molecular Biology, 31(2), 240-244.

Vancouver

Kas'yanenko NA, Nikolenko OV, Prokhorova SA, D'yachenko SA, Smorygo NA, Ivin BA и пр. Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands. Molecular Biology. 1997 Март;31(2):240-244.

Author

Kas'yanenko, N. A. ; Nikolenko, O. V. ; Prokhorova, S. A. ; D'yachenko, S. A. ; Smorygo, N. A. ; Ivin, B. A. ; Frisman, E. V. / Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands. в: Molecular Biology. 1997 ; Том 31, № 2. стр. 240-244.

BibTeX

@article{d3923b79771b4ec98404a97063d6e337,

title = "Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands",

abstract = "The interaction of DNA with coordination compounds of bivalent platinum containing 5-substituted uracil ligands (R = H, Br, NO2) was studied. For all title complexes, the mode of interaction with DNA in solution is virtually unaffected by the nature of the substituent. Ionic strength has only a slight effect on complex formation. The platinum compounds alter the optical anisotropy of DNA but have no influence on its circular dichroism and hydrodynamic parameters. It is assumed that the platinum complexes bind to the macromolecule so that the pyrimidine ligands are on the periphery of the double helix. It is possible in this case that the NH3 groups form hydrogen bonds with the phosphate oxygens.",

keywords = "DNA conformation, Pt(II) complexes, Pyrimidine ligands",

author = "Kas'yanenko, {N. A.} and Nikolenko, {O. V.} and Prokhorova, {S. A.} and D'yachenko, {S. A.} and Smorygo, {N. A.} and Ivin, {B. A.} and Frisman, {E. V.}",

year = "1997",

month = mar,

language = "English",

volume = "31",

pages = "240--244",

journal = "Molecular Biology",

issn = "0026-8933",

publisher = "Pleiades Publishing",

number = "2",

}

RIS

TY - JOUR

T1 - Interaction of DNA with coordination compounds of bivalent platinum. III. Platinum compounds with two pyrimidine ligands

AU - Kas'yanenko, N. A.

AU - Nikolenko, O. V.

AU - Prokhorova, S. A.

AU - D'yachenko, S. A.

AU - Smorygo, N. A.

AU - Ivin, B. A.

AU - Frisman, E. V.

PY - 1997/3

Y1 - 1997/3

N2 - The interaction of DNA with coordination compounds of bivalent platinum containing 5-substituted uracil ligands (R = H, Br, NO2) was studied. For all title complexes, the mode of interaction with DNA in solution is virtually unaffected by the nature of the substituent. Ionic strength has only a slight effect on complex formation. The platinum compounds alter the optical anisotropy of DNA but have no influence on its circular dichroism and hydrodynamic parameters. It is assumed that the platinum complexes bind to the macromolecule so that the pyrimidine ligands are on the periphery of the double helix. It is possible in this case that the NH3 groups form hydrogen bonds with the phosphate oxygens.

AB - The interaction of DNA with coordination compounds of bivalent platinum containing 5-substituted uracil ligands (R = H, Br, NO2) was studied. For all title complexes, the mode of interaction with DNA in solution is virtually unaffected by the nature of the substituent. Ionic strength has only a slight effect on complex formation. The platinum compounds alter the optical anisotropy of DNA but have no influence on its circular dichroism and hydrodynamic parameters. It is assumed that the platinum complexes bind to the macromolecule so that the pyrimidine ligands are on the periphery of the double helix. It is possible in this case that the NH3 groups form hydrogen bonds with the phosphate oxygens.

KW - DNA conformation

KW - Pt(II) complexes

KW - Pyrimidine ligands

UR - http://www.scopus.com/inward/record.url?scp=0031534859&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0031534859

VL - 31

SP - 240

EP - 244

JO - Molecular Biology

JF - Molecular Biology

SN - 0026-8933

IS - 2

ER -

ID: 73393675