Insulin resistance is one of the common signs of end-stage renal failure. The onset of hemodialysis is accompanied by an increase in the sensitivity of peripheral tissues to insulin, but it does not eliminate insulin resistance. Clamp test in dialysis patients is difficult to apply. There is currently no consensus on how to replace it. It has been suggested that it is advisable to use a combination of HOMA-IR-1, HOMA2% B, Quantitative insulin sensitivity check index (QUICKI).