Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Infrared Spectroscopy of Blood Serum from Patients with Oncohematological Diseases. / Тельная, Елизавета Андреевна; Плотникова, Людмила Валерьевна; Гарифуллин, Андрей; Кувшинов, Алексей; Волошин, С. В.; Поляничко, Александр Михайлович.
в: Biophysics, Том 65, № 6, 11.2020, стр. 981-986.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Infrared Spectroscopy of Blood Serum from Patients with Oncohematological Diseases
AU - Тельная, Елизавета Андреевна
AU - Плотникова, Людмила Валерьевна
AU - Гарифуллин, Андрей
AU - Кувшинов, Алексей
AU - Волошин, С. В.
AU - Поляничко, Александр Михайлович
PY - 2020/11
Y1 - 2020/11
N2 - A comparative analysis of the secondary structure of blood serum proteins was carried out in patients with multiple myeloma, chronic lymphocytic leukemia and in healthy donors. The secondary structure of proteins in serum was determined using an infrared spectroscopy method. It was demonstrated that the proposed approach allows one to register a decrease in the portion of α-helical regions and an increase in the number of β-sheets in the blood serum samples of patients with multiple myeloma compared with healthy donors and patients with chronic lymphocytic leukemia.
AB - A comparative analysis of the secondary structure of blood serum proteins was carried out in patients with multiple myeloma, chronic lymphocytic leukemia and in healthy donors. The secondary structure of proteins in serum was determined using an infrared spectroscopy method. It was demonstrated that the proposed approach allows one to register a decrease in the portion of α-helical regions and an increase in the number of β-sheets in the blood serum samples of patients with multiple myeloma compared with healthy donors and patients with chronic lymphocytic leukemia.
KW - Keywords: IR spectroscopy
KW - multiple myeloma
KW - protein secondary structure
UR - http://www.scopus.com/inward/record.url?scp=85102507181&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/8735795f-928d-3a0d-acd2-360c7afb0c10/
U2 - 10.1134/S0006350920060214
DO - 10.1134/S0006350920060214
M3 - Article
VL - 65
SP - 981
EP - 986
JO - Biophysics (Russian Federation)
JF - Biophysics (Russian Federation)
SN - 0006-3509
IS - 6
ER -
ID: 74884760