Результаты исследований: Научные публикации в периодических изданиях › статья
Influence of synthetic peptide inductors on antibacterial activity of enterococci. / Ermolenko, E.I.; Chernysh , A.; Kolobov, A.; Суворов, Александр Николаевич.
в: Beneficial microbes, Том 2, № 1, 2011, стр. 9-13.Результаты исследований: Научные публикации в периодических изданиях › статья
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TY - JOUR
T1 - Influence of synthetic peptide inductors on antibacterial activity of enterococci
AU - Ermolenko, E.I.
AU - Chernysh , A.
AU - Kolobov, A.
AU - Суворов, Александр Николаевич
PY - 2011
Y1 - 2011
N2 - Antibacterial activity of probiotic enterococci is often related to the production of bacteriocins. There is a variety of Enterococcus faecium strains which synthesise one or several enterocins including A, B, P, 96, L50AB and others. In this work we have analysed the probiotic strain E. faecium L3 whose genome contained the genes encoding enterocins А, В and a three-component regulatory system. All these genes were found to be expressed in enterococcal strain L3. Antimicrobial activity of the strain tested on the strains of Listeria monocytogenes and Streptococcus agalactiae was pheromone dependent. Chemically synthesised cyclic peptides (analogues and shorter derivates of EntF) with different molecular structures were able to increase the antagonistic activity of the strain E. faecium L3 in contrast to the strain E. faecium SF68, which does nоt have genes encoding enterocins А and В.
AB - Antibacterial activity of probiotic enterococci is often related to the production of bacteriocins. There is a variety of Enterococcus faecium strains which synthesise one or several enterocins including A, B, P, 96, L50AB and others. In this work we have analysed the probiotic strain E. faecium L3 whose genome contained the genes encoding enterocins А, В and a three-component regulatory system. All these genes were found to be expressed in enterococcal strain L3. Antimicrobial activity of the strain tested on the strains of Listeria monocytogenes and Streptococcus agalactiae was pheromone dependent. Chemically synthesised cyclic peptides (analogues and shorter derivates of EntF) with different molecular structures were able to increase the antagonistic activity of the strain E. faecium L3 in contrast to the strain E. faecium SF68, which does nоt have genes encoding enterocins А and В.
U2 - 10.3920/BM2010.0006
DO - 10.3920/BM2010.0006
M3 - Article
VL - 2
SP - 9
EP - 13
JO - Beneficial microbes
JF - Beneficial microbes
SN - 1876-2883
IS - 1
ER -
ID: 27880015