TY - JOUR

T1 - Immunity of the lugworm Arenicola marina: cells and molecules

AU - Berlov, M. N.

AU - Maltseva, A. L.

PY - 2016

Y1 - 2016

N2 - Immune responses of invertebrate animals are mediated through innate mechanisms, among which phagocytosis, encapsulation, production of ROS and antimicrobial peptides. Although polychetes represent an evolutionary interesting group closely related to presumable common ancestor of other celomates, their immune mechanisms still remain scarcely investigated. Here we discuss immune responses of the polychete Arenicola marina, the lugworm. Besides an overview of diversity of celomocytes and cellular responses, we present the synopsis on antimicrobial peptides arenicins: their structure, function and therapeutic potential.

AB - Immune responses of invertebrate animals are mediated through innate mechanisms, among which phagocytosis, encapsulation, production of ROS and antimicrobial peptides. Although polychetes represent an evolutionary interesting group closely related to presumable common ancestor of other celomates, their immune mechanisms still remain scarcely investigated. Here we discuss immune responses of the polychete Arenicola marina, the lugworm. Besides an overview of diversity of celomocytes and cellular responses, we present the synopsis on antimicrobial peptides arenicins: their structure, function and therapeutic potential.

KW - immunity

KW - celomocytes

KW - phagocytosis

KW - antimicrobial peptides

KW - arenicins

KW - polychetes

KW - lugworm

KW - Arenicola marina

M3 - Обзорная статья

VL - 13

SP - 247

EP - 256

JO - Invertebrate Survival Journal

JF - Invertebrate Survival Journal

SN - 1824-307X

ER -