Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Immediate results of isolated chemoperfusion of the lung with melphalan and cisplatin in combination with metastasectomy in treatment for resectable metastatic lung lesions. / Levchenko, E. V.; Kalinin, P. S.; Senchik, K. Yu; Mamontov, O. Yu; Gorokhov, L. V.; Barchuk, A. S.; Mishchenko, A. V.
в: Voprosy Onkologii, Том 61, № 6, 2015, стр. 960-964.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Immediate results of isolated chemoperfusion of the lung with melphalan and cisplatin in combination with metastasectomy in treatment for resectable metastatic lung lesions
AU - Levchenko, E. V.
AU - Kalinin, P. S.
AU - Senchik, K. Yu
AU - Mamontov, O. Yu
AU - Gorokhov, L. V.
AU - Barchuk, A. S.
AU - Mishchenko, A. V.
PY - 2015
Y1 - 2015
N2 - For treatment of metastatic lung lesions there was used the method of isolated chemoperfusion in combination with metastasectomy. The study included 74 patients (mean age 43 ± 13,4 years). There were performed 99 normothermic isolated chemoperfusions of the lung: with melphalan (39) and cisplatin (60). During surgery there were no lethality outcomes. In the immediate postoperative period it was recorded 1 (1.4%) death developed in 3 days after surgery. The cause of this death was postperfusion lung edema accompanied by increase of signs of respiratory insufficiency. There were following complications after isolated chemoperfusions of the lung: anemia - 23 (23.1%), nausea - 13 (13.1%), vomiting - 5 (5.1%), atrial fibrillation - 10 (10.1%), pneumonia - 2 (2.0%), pulmonary infarction - 2 (2.0%), chylothorax - 1 (1.0%), pneumothorax - 29 (29,3%), emphysema of soft tissues of the chest wall 73 (73,7%). Thus isolated chemoperfusion of the lung with melphalan or cisplatin is a procedure reproducible and relatively safe.
AB - For treatment of metastatic lung lesions there was used the method of isolated chemoperfusion in combination with metastasectomy. The study included 74 patients (mean age 43 ± 13,4 years). There were performed 99 normothermic isolated chemoperfusions of the lung: with melphalan (39) and cisplatin (60). During surgery there were no lethality outcomes. In the immediate postoperative period it was recorded 1 (1.4%) death developed in 3 days after surgery. The cause of this death was postperfusion lung edema accompanied by increase of signs of respiratory insufficiency. There were following complications after isolated chemoperfusions of the lung: anemia - 23 (23.1%), nausea - 13 (13.1%), vomiting - 5 (5.1%), atrial fibrillation - 10 (10.1%), pneumonia - 2 (2.0%), pulmonary infarction - 2 (2.0%), chylothorax - 1 (1.0%), pneumothorax - 29 (29,3%), emphysema of soft tissues of the chest wall 73 (73,7%). Thus isolated chemoperfusion of the lung with melphalan or cisplatin is a procedure reproducible and relatively safe.
KW - Cisplatin
KW - Isolated chemoperfusion of the lung
KW - Melphala
KW - Metastatic lung lesions
UR - http://www.scopus.com/inward/record.url?scp=84962607242&partnerID=8YFLogxK
M3 - статья
C2 - 26995987
AN - SCOPUS:84962607242
VL - 61
SP - 960
EP - 964
JO - Вопросы онкологии
JF - Вопросы онкологии
SN - 0507-3758
IS - 6
ER -
ID: 88744165