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IgSimulator : a versatile immunosequencing simulator. / Safonova, Y.; Lapidus, A.; Lill, J.

в: Bioinformatics, Том 31, № 19, 01.10.2015, стр. 3213-3215.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Safonova, Y. ; Lapidus, A. ; Lill, J. / IgSimulator : a versatile immunosequencing simulator. в: Bioinformatics. 2015 ; Том 31, № 19. стр. 3213-3215.

BibTeX

@article{61856f89e0fc4c528c2b8ca9bd47fe8b,
title = "IgSimulator: a versatile immunosequencing simulator",
abstract = "Motivation: The recent introduction of next-generation sequencing technologies to antibody studies have resulted in a growing number of immunoinformatics tools for antibody repertoire analysis. However, benchmarking these newly emerging tools remains problematic since the gold standard datasets that are needed to validate these tools are typically not available.Results: Since simulating antibody repertoires is often the only feasible way to benchmark new immunoinformatics tools, we developed the IgSimulator tool that addresses various complications in generating realistic antibody repertoires. IgSimulator's code has modular structure and can be easily adapted to new requirements to simulation.",
author = "Y. Safonova and A. Lapidus and J. Lill",
year = "2015",
month = oct,
day = "1",
doi = "10.1093/bioinformatics/btv326",
language = "Английский",
volume = "31",
pages = "3213--3215",
journal = "Bioinformatics",
issn = "1367-4803",
publisher = "Oxford University Press",
number = "19",

}

RIS

TY - JOUR

T1 - IgSimulator

T2 - a versatile immunosequencing simulator

AU - Safonova, Y.

AU - Lapidus, A.

AU - Lill, J.

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Motivation: The recent introduction of next-generation sequencing technologies to antibody studies have resulted in a growing number of immunoinformatics tools for antibody repertoire analysis. However, benchmarking these newly emerging tools remains problematic since the gold standard datasets that are needed to validate these tools are typically not available.Results: Since simulating antibody repertoires is often the only feasible way to benchmark new immunoinformatics tools, we developed the IgSimulator tool that addresses various complications in generating realistic antibody repertoires. IgSimulator's code has modular structure and can be easily adapted to new requirements to simulation.

AB - Motivation: The recent introduction of next-generation sequencing technologies to antibody studies have resulted in a growing number of immunoinformatics tools for antibody repertoire analysis. However, benchmarking these newly emerging tools remains problematic since the gold standard datasets that are needed to validate these tools are typically not available.Results: Since simulating antibody repertoires is often the only feasible way to benchmark new immunoinformatics tools, we developed the IgSimulator tool that addresses various complications in generating realistic antibody repertoires. IgSimulator's code has modular structure and can be easily adapted to new requirements to simulation.

U2 - 10.1093/bioinformatics/btv326

DO - 10.1093/bioinformatics/btv326

M3 - статья

VL - 31

SP - 3213

EP - 3215

JO - Bioinformatics

JF - Bioinformatics

SN - 1367-4803

IS - 19

ER -

ID: 5799342