Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Identification of Centromere-Specific Repeats in the Zebra Finch Genome. / Takki, Olga; Komissarov, Aleksey; Kulak, Maria; Galkina, Svetlana.
в: Cytogenetic and Genome Research, Том 162, № 1-2, 01.06.2022, стр. 55-63.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Identification of Centromere-Specific Repeats in the Zebra Finch Genome
AU - Takki, Olga
AU - Komissarov, Aleksey
AU - Kulak, Maria
AU - Galkina, Svetlana
N1 - Publisher Copyright: © 2022 The Author(s). Published by S. Karger AG, Basel.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - Tandem repetitive sequences represent a significant part of many genomes but remain poorly characterized due to various methodological difficulties. Here, we describe the tandem repeat composition in the genome of zebra finch, Taeniopygia guttata, a species that has long served as an animal model, primarily in neurobiology and comparative genomics. Using available genome sequencing raw read datasets, we bioinformatically reconstructed consensus sequences of several tandem repeats and proved that the most abundant ones, Tgut191A and Tgut716A, are centromere-associated in chromosomes. Each centromeric region can have a different number of copies of each repeat, with Tgut716A enrichment in almost all microchromosomes and sex chromosomes. Sequences similar to Tgut191A and Tgut716A found in other Estrildidae and Viduidae species can be considered as candidate centromeric sequences, but this requires further cytogenetic verification.
AB - Tandem repetitive sequences represent a significant part of many genomes but remain poorly characterized due to various methodological difficulties. Here, we describe the tandem repeat composition in the genome of zebra finch, Taeniopygia guttata, a species that has long served as an animal model, primarily in neurobiology and comparative genomics. Using available genome sequencing raw read datasets, we bioinformatically reconstructed consensus sequences of several tandem repeats and proved that the most abundant ones, Tgut191A and Tgut716A, are centromere-associated in chromosomes. Each centromeric region can have a different number of copies of each repeat, with Tgut716A enrichment in almost all microchromosomes and sex chromosomes. Sequences similar to Tgut191A and Tgut716A found in other Estrildidae and Viduidae species can be considered as candidate centromeric sequences, but this requires further cytogenetic verification.
KW - Birds
KW - Heterochromatin
KW - Satellite DNA
KW - Taeniopygia guttata
KW - Tandem repeats
UR - http://www.scopus.com/inward/record.url?scp=85127047140&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/18ba09fd-b51a-325a-8a9d-0572c1a3f0a9/
U2 - 10.1159/000521716
DO - 10.1159/000521716
M3 - Article
C2 - 35279659
AN - SCOPUS:85127047140
VL - 162
SP - 55
EP - 63
JO - Cytogenetic and Genome Research
JF - Cytogenetic and Genome Research
SN - 1424-8581
IS - 1-2
ER -
ID: 95001193