This study investigates a variety of lakes of different origin in the Siberian Lena River delta for lake hydrological, hydrochemical, and morphometric characteristics. The results are based on in-situ field measurements and subsequent water sample analyses. Significant differences between the characteristics of polygonal ponds, thermokarst and oxbow lakes, and lakes influenced by sea-water are revealed. The differences in hydrochemical characteristics are explained by differences in the lakes’ specific locations and relief settings, hydrological regimes, and origins.