TY - JOUR

T1 - Humic substances as an environmental- friendly organic wastes potentially help as natural anti-virus to inhibit COVID-19

AU - Hafez, Mohamed

AU - Popov, Alexander I.

AU - Zelenkov, Valery N.

AU - Teplyakova, Tamara V.

AU - Rashad, Mohamed

PY - 2020

Y1 - 2020

N2 - The aim of this review was trying to access information to help the world in getting rid of a nightmare COVID-19, by evaluatingthe anti-virus activity of humic substances as natural anti-virus to inhibit COVID-19. In this scientific review, which devoted tobiomedical aspects of various origin humic substances and other organic wastes influences on living organisms, is presented. It isshown that kinds of biological activity of humic substances (HS) are an integral indicator of properties of these substances. Dataon humic substances and melanin of anti-viral, anti-carcinogen, and anti-virus diseases such as (COVID-19) activity is given tooby immune-modulation. Humic substances, or humates, are the end points of organic (carbon-containing) degradation. They’reessentially what are left over from microbial decomposition of organisms and dead plant matter; however, they remain highlyconcentrated in minerals, amino acids, and fatty acids. Studies have shown that humic substances are effective against both nakedand enveloped DNA viruses, including Coxsackie A9, influenza A and B, and herpes simplex type 1 and 2 viruses. In conclusion,humic substances effected on reduce oxidative stress and even induce apoptosis in hepatic cancer lines. humic substances areshown to also influence the micro-biome and possibly improve gut function. This will help make conclusive statements regardinghumic substances function and its influence on immune-related diseases. The mechanism whereby humic substances inhibit thecytopathicity of a number of viruses has been studied in some depth. It is thought that the materials prevent viral replicating bysorbing onto the viral envelope protein and thereby blocking the sorption of viral particles to cell surfaces.

AB - The aim of this review was trying to access information to help the world in getting rid of a nightmare COVID-19, by evaluatingthe anti-virus activity of humic substances as natural anti-virus to inhibit COVID-19. In this scientific review, which devoted tobiomedical aspects of various origin humic substances and other organic wastes influences on living organisms, is presented. It isshown that kinds of biological activity of humic substances (HS) are an integral indicator of properties of these substances. Dataon humic substances and melanin of anti-viral, anti-carcinogen, and anti-virus diseases such as (COVID-19) activity is given tooby immune-modulation. Humic substances, or humates, are the end points of organic (carbon-containing) degradation. They’reessentially what are left over from microbial decomposition of organisms and dead plant matter; however, they remain highlyconcentrated in minerals, amino acids, and fatty acids. Studies have shown that humic substances are effective against both nakedand enveloped DNA viruses, including Coxsackie A9, influenza A and B, and herpes simplex type 1 and 2 viruses. In conclusion,humic substances effected on reduce oxidative stress and even induce apoptosis in hepatic cancer lines. humic substances areshown to also influence the micro-biome and possibly improve gut function. This will help make conclusive statements regardinghumic substances function and its influence on immune-related diseases. The mechanism whereby humic substances inhibit thecytopathicity of a number of viruses has been studied in some depth. It is thought that the materials prevent viral replicating bysorbing onto the viral envelope protein and thereby blocking the sorption of viral particles to cell surfaces.

KW - Environmental-friendly

KW - humic substances

KW - biological activity and immune-modulation

UR - http://sciencearchives.org/wp-content/uploads/2020/09/Science-Archives-2020-Vol.-1-2-53-60.pdf

M3 - Review article

VL - 1

SP - 53

EP - 60

JO - Science Archives

JF - Science Archives

SN - 2454-1354

IS - 2

ER -