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Hidden symmetries of DNA molecule. / Tulub, Alexander A.; Stefanov, Vassily E.

в: Journal of Theoretical Biology, Том 416, 07.03.2017, стр. 144-148.

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Tulub, Alexander A. ; Stefanov, Vassily E. / Hidden symmetries of DNA molecule. в: Journal of Theoretical Biology. 2017 ; Том 416. стр. 144-148.

BibTeX

@article{99a8bc26663d46ab84a091ef408e4578,
title = "Hidden symmetries of DNA molecule",
abstract = "Despite the fact that DNA molecule is studied up and down, we know very little about the role of DNA triplets in coding amino acids and stop-codons. The paper aims to fill this gap through attracting spintronic ideas and carrying out QM/MM computations on a full-turn DNA fragment. The computations reveal two hidden symmetries: the spin splitting (the Rashba effect), confined within each triplet, and the quantum “phase” link between the triplet nature (in total, 64 triplets) and the corresponding amino acid and three stop-codons. The hidden symmetries become evident upon binding the magnesium cofactor to DNA triplets in 5{\textquoteright}−3{\textquoteright} and 3{\textquoteright}−5{\textquoteright} directions.",
keywords = "DNA molecule, Genetic code, Hidden symmetries, Nucleotide triplets, QM/MM computations, Spin physics",
author = "Tulub, {Alexander A.} and Stefanov, {Vassily E.}",
note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",
year = "2017",
month = mar,
day = "7",
doi = "10.1016/j.jtbi.2017.01.001",
language = "English",
volume = "416",
pages = "144--148",
journal = "Journal of Theoretical Biology",
issn = "0022-5193",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Hidden symmetries of DNA molecule

AU - Tulub, Alexander A.

AU - Stefanov, Vassily E.

N1 - Publisher Copyright: © 2017 Elsevier Ltd

PY - 2017/3/7

Y1 - 2017/3/7

N2 - Despite the fact that DNA molecule is studied up and down, we know very little about the role of DNA triplets in coding amino acids and stop-codons. The paper aims to fill this gap through attracting spintronic ideas and carrying out QM/MM computations on a full-turn DNA fragment. The computations reveal two hidden symmetries: the spin splitting (the Rashba effect), confined within each triplet, and the quantum “phase” link between the triplet nature (in total, 64 triplets) and the corresponding amino acid and three stop-codons. The hidden symmetries become evident upon binding the magnesium cofactor to DNA triplets in 5’−3’ and 3’−5’ directions.

AB - Despite the fact that DNA molecule is studied up and down, we know very little about the role of DNA triplets in coding amino acids and stop-codons. The paper aims to fill this gap through attracting spintronic ideas and carrying out QM/MM computations on a full-turn DNA fragment. The computations reveal two hidden symmetries: the spin splitting (the Rashba effect), confined within each triplet, and the quantum “phase” link between the triplet nature (in total, 64 triplets) and the corresponding amino acid and three stop-codons. The hidden symmetries become evident upon binding the magnesium cofactor to DNA triplets in 5’−3’ and 3’−5’ directions.

KW - DNA molecule

KW - Genetic code

KW - Hidden symmetries

KW - Nucleotide triplets

KW - QM/MM computations

KW - Spin physics

UR - http://www.scopus.com/inward/record.url?scp=85009363512&partnerID=8YFLogxK

U2 - 10.1016/j.jtbi.2017.01.001

DO - 10.1016/j.jtbi.2017.01.001

M3 - Article

C2 - 28077290

VL - 416

SP - 144

EP - 148

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

ER -

ID: 7734131