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Glycopolymer-graft-polypeptide copolymers as potential carriers for nucleic acids. / Гладнев, Сергей Владиславович; Левит, М. Л.; Тенникова, Татьяна Борисовна; Коржикова-Влах, Евгения Георгиевна.

в: Mendeleev Communications, Том 35, № 3, 01.01.2025, стр. 295-298.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Гладнев, Сергей Владиславович ; Левит, М. Л. ; Тенникова, Татьяна Борисовна ; Коржикова-Влах, Евгения Георгиевна. / Glycopolymer-graft-polypeptide copolymers as potential carriers for nucleic acids. в: Mendeleev Communications. 2025 ; Том 35, № 3. стр. 295-298.

BibTeX

@article{a8ade2cc1a514b4980f252ea78839bdb,
title = "Glycopolymer-graft-polypeptide copolymers as potential carriers for nucleic acids.",
abstract = "Bioinspired copolymers consisting of a glycopolymer main chain grafted with polylysine were synthesized using metal-free click chemistry based on a 1,3-dipolar cycloaddition reaction involving strained cyclic alkyne. Poly(2-deoxy-2-methacrylamido-d-glucose)-graft-polylysine was efficiently complexed with a double-stranded oligonucleotide duplex. The cytotoxicity of the polyplex was lower than that of the free copolymer.",
keywords = "bioinspired copolymers, delivery systems, graft copolymers, metal-free click chemistry, nucleic acids, polypeptides, synthetic glycopolymers",
author = "Гладнев, {Сергей Владиславович} and Левит, {М. Л.} and Тенникова, {Татьяна Борисовна} and Коржикова-Влах, {Евгения Георгиевна}",
year = "2025",
month = jan,
day = "1",
doi = "10.71267/mencom.7606",
language = "English",
volume = "35",
pages = "295--298",
journal = "Mendeleev Communications",
issn = "0959-9436",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Glycopolymer-graft-polypeptide copolymers as potential carriers for nucleic acids.

AU - Гладнев, Сергей Владиславович

AU - Левит, М. Л.

AU - Тенникова, Татьяна Борисовна

AU - Коржикова-Влах, Евгения Георгиевна

PY - 2025/1/1

Y1 - 2025/1/1

N2 - Bioinspired copolymers consisting of a glycopolymer main chain grafted with polylysine were synthesized using metal-free click chemistry based on a 1,3-dipolar cycloaddition reaction involving strained cyclic alkyne. Poly(2-deoxy-2-methacrylamido-d-glucose)-graft-polylysine was efficiently complexed with a double-stranded oligonucleotide duplex. The cytotoxicity of the polyplex was lower than that of the free copolymer.

AB - Bioinspired copolymers consisting of a glycopolymer main chain grafted with polylysine were synthesized using metal-free click chemistry based on a 1,3-dipolar cycloaddition reaction involving strained cyclic alkyne. Poly(2-deoxy-2-methacrylamido-d-glucose)-graft-polylysine was efficiently complexed with a double-stranded oligonucleotide duplex. The cytotoxicity of the polyplex was lower than that of the free copolymer.

KW - bioinspired copolymers

KW - delivery systems

KW - graft copolymers

KW - metal-free click chemistry

KW - nucleic acids

KW - polypeptides

KW - synthetic glycopolymers

UR - https://www.mendeley.com/catalogue/f1b82804-fa06-3965-b066-0e61ee04906e/

U2 - 10.71267/mencom.7606

DO - 10.71267/mencom.7606

M3 - Article

VL - 35

SP - 295

EP - 298

JO - Mendeleev Communications

JF - Mendeleev Communications

SN - 0959-9436

IS - 3

ER -

ID: 134067433