This article compares the radical rejection of metaphysics in the work of Gilles Deleuze with Zen Buddhism. Tbe author proposes the theses that the rejection of metaphysics opens the new perspective for the description of reality and new philosophical spaces, and the same radicality of this nihilistic gesture is necessary as the first moment of a new philosophical synthesis. Principal attention is devoted to the conceptual apparatus that Deleuze applies to the deconstruction of metaphysics. The turn of the Western Philosophy to the East is a subject that has not yet received adequate elaboration. The detailed description of pli in the philosophy of Gilles Deleuze does not occur at the level of a new ontological program. So, we can talk only about the criticism of the metaphysics of the present and the original gesture that permits him to proclaim the philosophy of the surface. Deleuze's thought develops its success from the immediate emotional influence that is not a rejection of thought but in its character is similar with satori of Zen Buddhism. The radical gesture of the Zen Buddhism consists in the purification of the conscience of all of the actual consistency and the eruption of the discursive flux. The philosophy of Gilles Deleuze includes the intellectual preparation and the interruption of the flow of thoughts and its non-finality. This non-finality of philosophical consideration has many consequences in different realms; they amount to the radical rejection of phenomenology and the rejection of teleology with its idea of the end of the history and the discovery of the new space for new philosophical synthesis. Refs 5.