Результаты исследований: Научные публикации в периодических изданиях › Обзор литературы
Genetic and environmental modulation of neurodevelopmental disorders: Translational insights from labs to beds. / Homberg, J. R.; Kyzar, E. J.; Scattoni, M. L.; Norton, W. H.; Pittman, J.; Gaikwad, S.; Nguyen, M.; Poudel, M. K.; Ullmann, J. F.; Diamond, D. M.; Kaluyeva, A. A.; Parker, M. O.; Brown, R. E.; Song, C.; Gainetdinov, R. R.; Gottesman, I. I.; Kalueff, A. V.
в: Brain Research Bulletin, № 125, 2016, стр. 79-91.Результаты исследований: Научные публикации в периодических изданиях › Обзор литературы
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TY - JOUR
T1 - Genetic and environmental modulation of neurodevelopmental disorders: Translational insights from labs to beds.
AU - Homberg, J. R.
AU - Kyzar, E. J.
AU - Scattoni, M. L.
AU - Norton, W. H.
AU - Pittman, J.
AU - Gaikwad, S.
AU - Nguyen, M.
AU - Poudel, M. K.
AU - Ullmann, J. F.
AU - Diamond, D. M.
AU - Kaluyeva, A. A.
AU - Parker, M. O.
AU - Brown, R. E.
AU - Song, C.
AU - Gainetdinov, R. R.
AU - Gottesman, I. I.
AU - Kalueff, A. V.
PY - 2016
Y1 - 2016
N2 - Neurodevelopmental disorders (NDDs) are a heterogeneous group of prevalent neuropsychiatric illnesses with various degrees of social, cognitive, motor, language and affective deficits. NDDs are caused by aberrant brain development due to genetic and environmental perturbations. Common NDDs include autism spectrum disorder (ASD), intellectual disability, communication/speech disorders, motor/tic disorders and attention deficit hyperactivity disorder. Genetic and epigenetic/environmental factors play a key role in these NDDs with significant societal impact. Given the lack of their efficient therapies, it is important to gain further translational insights into the pathobiology of NDDs. To address these challenges, the International Stress and Behavior Society (ISBS) has established the Strategic Task Force on NDDs. Summarizing the Panel's findings, here we discuss the neurobiological mechanisms of selected common NDDs and a wider NDD+ spectrum of associated neuropsychiatric disorders with developmental traject
AB - Neurodevelopmental disorders (NDDs) are a heterogeneous group of prevalent neuropsychiatric illnesses with various degrees of social, cognitive, motor, language and affective deficits. NDDs are caused by aberrant brain development due to genetic and environmental perturbations. Common NDDs include autism spectrum disorder (ASD), intellectual disability, communication/speech disorders, motor/tic disorders and attention deficit hyperactivity disorder. Genetic and epigenetic/environmental factors play a key role in these NDDs with significant societal impact. Given the lack of their efficient therapies, it is important to gain further translational insights into the pathobiology of NDDs. To address these challenges, the International Stress and Behavior Society (ISBS) has established the Strategic Task Force on NDDs. Summarizing the Panel's findings, here we discuss the neurobiological mechanisms of selected common NDDs and a wider NDD+ spectrum of associated neuropsychiatric disorders with developmental traject
KW - Experimental model
KW - Model organism
KW - Neurodevelopmental disorder
KW - Preclinical study
KW - Translational research
U2 - 10.1016/j.brainresbull.2016.04.015
DO - 10.1016/j.brainresbull.2016.04.015
M3 - Literature review
SP - 79
EP - 91
JO - Brain Research Bulletin
JF - Brain Research Bulletin
SN - 0361-9230
IS - 125
ER -
ID: 7590002