Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
GABA metabolism in the mouse brain after exposure of head to 60Co-γ-rays. / Savitskii, I. V.; Rozanov, V. A.
в: Radiobiologiya, Том 19, № 4, 01.01.1979, стр. 532-536.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - GABA metabolism in the mouse brain after exposure of head to 60Co-γ-rays
AU - Savitskii, I. V.
AU - Rozanov, V. A.
PY - 1979/1/1
Y1 - 1979/1/1
N2 - A study was made of the content of gamma-aminobutyric acid (GABA) glutamate and the total of aspartate+asparagine+glutamine, and activity of glutamatedecarboxylase and GABA-α-ketoglutarate aminotransferase in the mouse brain after exposure of head to 1500 R of 60Co-γ-rays. GABA content gradually increases shortly after exposure, and glutamate content decreases at later times following irradiation. The activity of both enzymes diminishes: in the case of GABA-transaminase, however, the diminution proceeded slower and lasted longer. The role of shifts in the GABA system in the development of damages to the nervous system after local exposure is discussed.
AB - A study was made of the content of gamma-aminobutyric acid (GABA) glutamate and the total of aspartate+asparagine+glutamine, and activity of glutamatedecarboxylase and GABA-α-ketoglutarate aminotransferase in the mouse brain after exposure of head to 1500 R of 60Co-γ-rays. GABA content gradually increases shortly after exposure, and glutamate content decreases at later times following irradiation. The activity of both enzymes diminishes: in the case of GABA-transaminase, however, the diminution proceeded slower and lasted longer. The role of shifts in the GABA system in the development of damages to the nervous system after local exposure is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0018725207&partnerID=8YFLogxK
M3 - Article
C2 - 504595
AN - SCOPUS:0018725207
VL - 19
SP - 532
EP - 536
JO - РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ
JF - РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ
SN - 0869-8031
IS - 4
ER -
ID: 42772285