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From past to future: suppressor mutations in yeast genes encoding translation termination factors. / Trubitsina, Nina; Zemlyanko, Olga; Moskalenko, Svetlana; Zhouravleva, Galina.

в: Biological Communications, Том 64, № 2, 2019, стр. 89-109.

Результаты исследований: Научные публикации в периодических изданияхстатья

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Trubitsina, Nina ; Zemlyanko, Olga ; Moskalenko, Svetlana ; Zhouravleva, Galina. / From past to future: suppressor mutations in yeast genes encoding translation termination factors. в: Biological Communications. 2019 ; Том 64, № 2. стр. 89-109.

BibTeX

@article{a50572cbd6b446e0a881707825d5e545,
title = "From past to future: suppressor mutations in yeast genes encoding translation termination factors.",
abstract = "The study of the SUP45 and SUP35 genes of yeast Saccharomyces cerevisiae in the laboratory of Physiological Genetics of St. Petersburg State University began in 1964 when the first omnipotent nonsense suppressor mutations were obtained. During the following 55 years, a lot of information about these genes has been gained through the research efforts of various laboratories. Now we know that SUP45 and SUP35 encode translation termination factors eRF1 and eRF3, respectively. Both genes are essential, and sup45 and sup35 mutations lead not only to impaired translation but also to multiple pleiotropic effects. The aim of this review is to summarize known data about suppressor mutations in SUP45 or SUP35 genes.",
keywords = "[PSI+] prion, eRF1, eRF3, Missense mutations, nonsense mutations, S. cerevisiae, Sup35, Sup45, suppression, Translation termination, [PSI+] prion, eRF1, eRF3, Missense mutations, nonsense mutations, S. cerevisiae, Sup35, Sup45, suppression, Translation termination",
author = "Nina Trubitsina and Olga Zemlyanko and Svetlana Moskalenko and Galina Zhouravleva",
year = "2019",
language = "English",
volume = "64",
pages = "89--109",
journal = "Biological Communications",
issn = "2542-2154",
publisher = "Издательство Санкт-Петербургского университета",
number = "2",

}

RIS

TY - JOUR

T1 - From past to future: suppressor mutations in yeast genes encoding translation termination factors.

AU - Trubitsina, Nina

AU - Zemlyanko, Olga

AU - Moskalenko, Svetlana

AU - Zhouravleva, Galina

PY - 2019

Y1 - 2019

N2 - The study of the SUP45 and SUP35 genes of yeast Saccharomyces cerevisiae in the laboratory of Physiological Genetics of St. Petersburg State University began in 1964 when the first omnipotent nonsense suppressor mutations were obtained. During the following 55 years, a lot of information about these genes has been gained through the research efforts of various laboratories. Now we know that SUP45 and SUP35 encode translation termination factors eRF1 and eRF3, respectively. Both genes are essential, and sup45 and sup35 mutations lead not only to impaired translation but also to multiple pleiotropic effects. The aim of this review is to summarize known data about suppressor mutations in SUP45 or SUP35 genes.

AB - The study of the SUP45 and SUP35 genes of yeast Saccharomyces cerevisiae in the laboratory of Physiological Genetics of St. Petersburg State University began in 1964 when the first omnipotent nonsense suppressor mutations were obtained. During the following 55 years, a lot of information about these genes has been gained through the research efforts of various laboratories. Now we know that SUP45 and SUP35 encode translation termination factors eRF1 and eRF3, respectively. Both genes are essential, and sup45 and sup35 mutations lead not only to impaired translation but also to multiple pleiotropic effects. The aim of this review is to summarize known data about suppressor mutations in SUP45 or SUP35 genes.

KW - [PSI+] prion

KW - eRF1

KW - eRF3

KW - Missense mutations

KW - nonsense mutations

KW - S. cerevisiae

KW - Sup35

KW - Sup45

KW - suppression

KW - Translation termination

KW - [PSI+] prion

KW - eRF1

KW - eRF3

KW - Missense mutations

KW - nonsense mutations

KW - S. cerevisiae

KW - Sup35

KW - Sup45

KW - suppression

KW - Translation termination

M3 - Article

VL - 64

SP - 89

EP - 109

JO - Biological Communications

JF - Biological Communications

SN - 2542-2154

IS - 2

ER -

ID: 78489615