Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Frequency-contrast sensitivity of visual stimulus perception in patients with schizophrenia treated with atypical and typical antipsychotics. / Shoshina, I. I.; Shelepin, Yu E.; Semenova, N. B.
в: Human Physiology, Том 40, № 1, 01.01.2014, стр. 35-39.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Frequency-contrast sensitivity of visual stimulus perception in patients with schizophrenia treated with atypical and typical antipsychotics
AU - Shoshina, I. I.
AU - Shelepin, Yu E.
AU - Semenova, N. B.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The effects of typical and atypical antipsychotics on the perception of visual stimuli that preferentially activate magnocellular or parvocellular visual channels have been studied. The threshold contrast sensitivity in healthy individuals and patients with schizophrenia has been recorded. The Gabor-like sinusoidal brightness gratings and spatial frequencies of 0.4, 3.6, and 17.9 cycles/degree were presented to the tested objects. The patients were divided into two groups, one receiving the therapy with atypical antipsychotics, and the other, with typical ones. The contrast sensitivity for low and medium spatial frequencies (i.e., for the stimuli corresponding to magnocellular channels) decreased compared to the norm. Note that the decrease in the contrast sensitivity for the low spatial frequencies in the patients treated with atypical antipsychotics is significantly more pronounced compared to the cohort that received typical antipsychotics.
AB - The effects of typical and atypical antipsychotics on the perception of visual stimuli that preferentially activate magnocellular or parvocellular visual channels have been studied. The threshold contrast sensitivity in healthy individuals and patients with schizophrenia has been recorded. The Gabor-like sinusoidal brightness gratings and spatial frequencies of 0.4, 3.6, and 17.9 cycles/degree were presented to the tested objects. The patients were divided into two groups, one receiving the therapy with atypical antipsychotics, and the other, with typical ones. The contrast sensitivity for low and medium spatial frequencies (i.e., for the stimuli corresponding to magnocellular channels) decreased compared to the norm. Note that the decrease in the contrast sensitivity for the low spatial frequencies in the patients treated with atypical antipsychotics is significantly more pronounced compared to the cohort that received typical antipsychotics.
KW - contrast-frequency sensitivity
KW - dopamine
KW - Gabor elements
KW - parvocellular and magnocellular visual channels
KW - schizophrenia
KW - serotonin
KW - typical and atypical antipsychotics
KW - visual perception
UR - http://www.scopus.com/inward/record.url?scp=84893968558&partnerID=8YFLogxK
U2 - 10.1134/S0362119714010150
DO - 10.1134/S0362119714010150
M3 - Article
AN - SCOPUS:84893968558
VL - 40
SP - 35
EP - 39
JO - Human Physiology
JF - Human Physiology
SN - 0362-1197
IS - 1
ER -
ID: 51465587