TY - JOUR

T1 - Free radical oxidation and antioxidant activity in placental tissue in preterm labor

AU - Prokopenko, V. M.

AU - Arutyunyan, A. V.

AU - Frolova, E. V.

AU - Kuz'minykh, T. U.

AU - Ailamazyan, E. K.

PY - 1997/12

Y1 - 1997/12

N2 - Effect of specific scavengers of reactive oxygen species on free-radical oxidation is studied in central and peripheral zones of the placenta from preterm delivering women (32-36 weeks) using the chemiluminescence method. A lower contribution of hypochlorite into free-radical processes and a reduced content of nonprotein SH-groups in the placenta are observed, superoxide dismutase, catalase, and total antioxidant activity being unchanged. It can be assumed that the reduced contribution of hypochlorite into free-radical processes is partially responsible for impaired antimicrobial barrier between mother and fetus in preterm labor.

AB - Effect of specific scavengers of reactive oxygen species on free-radical oxidation is studied in central and peripheral zones of the placenta from preterm delivering women (32-36 weeks) using the chemiluminescence method. A lower contribution of hypochlorite into free-radical processes and a reduced content of nonprotein SH-groups in the placenta are observed, superoxide dismutase, catalase, and total antioxidant activity being unchanged. It can be assumed that the reduced contribution of hypochlorite into free-radical processes is partially responsible for impaired antimicrobial barrier between mother and fetus in preterm labor.

KW - Antioxidant activity

KW - Chemiluminescence

KW - Free-radical oxidation

KW - Placenta

KW - Preterm labor

UR - http://www.scopus.com/inward/record.url?scp=28544433389&partnerID=8YFLogxK

U2 - 10.1007/bf02445114

DO - 10.1007/bf02445114

M3 - Article

AN - SCOPUS:28544433389

VL - 124

SP - 1182

EP - 1184

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 6

ER -