Результаты исследований: Научные публикации в периодических изданиях › статья
Facile synthesis of pyrido[2,3-d]pyrimidines via cyclocondensation of 4,6-dichloro-2-methylsulfanylpyrimidine-5-carbaldehyde with β-substituted β-aminoacrylic esters. / Chizhova, M.E.; Bakulina, O.Yu.; Ivanov, A.Yu.; Lobanov, P.S.; Dar'in, D.V.
в: Tetrahedron, Том 71, № 36, 2015, стр. 6196-6203.Результаты исследований: Научные публикации в периодических изданиях › статья
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TY - JOUR
T1 - Facile synthesis of pyrido[2,3-d]pyrimidines via cyclocondensation of 4,6-dichloro-2-methylsulfanylpyrimidine-5-carbaldehyde with β-substituted β-aminoacrylic esters
AU - Chizhova, M.E.
AU - Bakulina, O.Yu.
AU - Ivanov, A.Yu.
AU - Lobanov, P.S.
AU - Dar'in, D.V.
PY - 2015
Y1 - 2015
N2 - A new facile synthesis of pyrido[2,3-d]pyrimidin-4-ones via cyclocondensation of 4,6-dichloro-2-methylsulfanylpyrimidine-5-carbaldehyde with beta-alkyl and beta-aryl-beta-aminoacrylic esters followed by hydrolysis of chlorine atom at position 4 of pyridopyrimidine ring has been developed. The cyclocondensation was found to be accelerated by acid. (C) 2015 Elsevier Ltd. All rights reserved.
AB - A new facile synthesis of pyrido[2,3-d]pyrimidin-4-ones via cyclocondensation of 4,6-dichloro-2-methylsulfanylpyrimidine-5-carbaldehyde with beta-alkyl and beta-aryl-beta-aminoacrylic esters followed by hydrolysis of chlorine atom at position 4 of pyridopyrimidine ring has been developed. The cyclocondensation was found to be accelerated by acid. (C) 2015 Elsevier Ltd. All rights reserved.
U2 - 10.1016/j.tet.2015.06.085
DO - 10.1016/j.tet.2015.06.085
M3 - Article
VL - 71
SP - 6196
EP - 6203
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 36
ER -
ID: 3974625