Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Experimental Zebrafish Models of Mitochondrial Dysfunction in the Pathogenesis of CNS Diseases. / Юшко, Л.В.; Котова, Мария Михайловна; Вьюнова, Т.В.; Калуев, Алан Валерьевич.
в: Journal of Evolutionary Biochemistry and Physiology, Том 59, № 6, 09.01.2024, стр. 2114-2128.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Experimental Zebrafish Models of Mitochondrial Dysfunction in the Pathogenesis of CNS Diseases
AU - Юшко, Л.В.
AU - Котова, Мария Михайловна
AU - Вьюнова, Т.В.
AU - Калуев, Алан Валерьевич
N1 - Yushko, L.V., Kotova, M.M., Vyunova, T.V. et al. Experimental Zebrafish Models of Mitochondrial Dysfunction in the Pathogenesis of CNS Diseases. J Evol Biochem Phys 59, 2114–2128 (2023). https://doi.org/10.1134/S0022093023060170
PY - 2024/1/9
Y1 - 2024/1/9
N2 - Mitochondrial dysfunctions are associated with pathogenesis of various brain disorders, including Alzheimer’s, Parkinson’s and Huntington’s diseases, amyotrophic lateral sclerosis, Leigh syndrome, and autism spectrum disorder. For studying mitochondrial dysfunction, as well as developing and testing new therapeutic strategies, in vivo studies on zebrafish (Danio rerio) are of particular interest due to their biological characteristics, practical laboratory maintenance, and high throughput. Here, we address genetic and pharmacological models of common mitochondrial dysfunctions and related neurological disorders in rodents and zebrafish, focusing of the growing utility of these fish in modeling mitochondrial pathogenesis of various CNS diseases.
AB - Mitochondrial dysfunctions are associated with pathogenesis of various brain disorders, including Alzheimer’s, Parkinson’s and Huntington’s diseases, amyotrophic lateral sclerosis, Leigh syndrome, and autism spectrum disorder. For studying mitochondrial dysfunction, as well as developing and testing new therapeutic strategies, in vivo studies on zebrafish (Danio rerio) are of particular interest due to their biological characteristics, practical laboratory maintenance, and high throughput. Here, we address genetic and pharmacological models of common mitochondrial dysfunctions and related neurological disorders in rodents and zebrafish, focusing of the growing utility of these fish in modeling mitochondrial pathogenesis of various CNS diseases.
UR - https://www.mendeley.com/catalogue/b0942c2b-1c27-3601-9d0b-c72e8f3e9335/
U2 - 10.1134/s0022093023060170
DO - 10.1134/s0022093023060170
M3 - Article
VL - 59
SP - 2114
EP - 2128
JO - Journal of Evolutionary Biochemistry and Physiology
JF - Journal of Evolutionary Biochemistry and Physiology
SN - 0022-0930
IS - 6
ER -
ID: 113769965