TY - JOUR

T1 - Evolution of 14-3-3 proteins in angiosperm plants: Recurring gene duplication and loss

AU - Михайлова, Юлия Владимировна

AU - Пузанский, Роман Константинович

AU - Шишова, Мария Федоровна

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/12/11

Y1 - 2021/12/11

N2 - 14-3-3 proteins are key regulatory factors in plants and are involved in a broad range of physiological processes. We addressed the evolutionary history of 14-3-3s from 46 angiosperm species, including basal angiosperm Amborella and major lineage of monocotyledons and eudicotyledons. Orthologs of Arabidopsis isoforms were detected. There were several rounds of duplication events in the evolutionary history of the 14-3-3 protein family in plants. At least four subfamilies (iota, epsilon, kappa, and psi) formed as a result of ancient duplication in a common ancestor of angiosperm plants. Recent duplication events followed by gene loss in plant lineage, among others Brassicaceae, Fabaceae, and Poaceae, further shaped the high diversity of 14-3-3 isoforms in plants. Coexpression data showed that 14-3-3 proteins formed different functional groups in different species. In some species, evolutionarily related groups of 14-3-3 proteins had coexpressed together under certain physiological conditions, whereas in other species, closely related isoforms expressed in the opposite manner. A possible explanation is that gene duplication and loss is accompanied by functional plasticity of 14-3-3 proteins.

AB - 14-3-3 proteins are key regulatory factors in plants and are involved in a broad range of physiological processes. We addressed the evolutionary history of 14-3-3s from 46 angiosperm species, including basal angiosperm Amborella and major lineage of monocotyledons and eudicotyledons. Orthologs of Arabidopsis isoforms were detected. There were several rounds of duplication events in the evolutionary history of the 14-3-3 protein family in plants. At least four subfamilies (iota, epsilon, kappa, and psi) formed as a result of ancient duplication in a common ancestor of angiosperm plants. Recent duplication events followed by gene loss in plant lineage, among others Brassicaceae, Fabaceae, and Poaceae, further shaped the high diversity of 14-3-3 isoforms in plants. Coexpression data showed that 14-3-3 proteins formed different functional groups in different species. In some species, evolutionarily related groups of 14-3-3 proteins had coexpressed together under certain physiological conditions, whereas in other species, closely related isoforms expressed in the opposite manner. A possible explanation is that gene duplication and loss is accompanied by functional plasticity of 14-3-3 proteins.

KW - 14-3-3 белки; полногеномная дупликация; коэкспрессия; семейство генов; молекулярная филогения; MrBayes

KW - 14-3-3 proteins

KW - Coexpression

KW - Gene family

KW - Molecular phylogeny

KW - MrBayes

KW - Whole-genome duplication

UR - http://www.scopus.com/inward/record.url?scp=85121439297&partnerID=8YFLogxK

U2 - 10.3390/plants10122724

DO - 10.3390/plants10122724

M3 - Article

C2 - 34961196

VL - 10

JO - Plants

JF - Plants

SN - 2223-7747

IS - 12

M1 - 2724

ER -