Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
ПEPCOHAЛИЗИPOВAHHAЯ ХИPУPГИЯ ВИCOЧHOЙ ЭПИЛEПCИИ У ДEТEЙ. / Abramov, K. B.; Mamatkhanov, M. R.; Lebedev, K. E.; Samochernykh, K. A.; Khachatryan, W. A.; Ratnikov, V. A.
в: Medical News of North Caucasus, Том 17, № 2, 2022, стр. 163-167.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - ПEPCOHAЛИЗИPOВAHHAЯ ХИPУPГИЯ ВИCOЧHOЙ ЭПИЛEПCИИ У ДEТEЙ
AU - Abramov, K. B.
AU - Mamatkhanov, M. R.
AU - Lebedev, K. E.
AU - Samochernykh, K. A.
AU - Khachatryan, W. A.
AU - Ratnikov, V. A.
N1 - Publisher Copyright: © Group of authors, 2022.
PY - 2022
Y1 - 2022
N2 - Eighty patients with symptomatic drug-resistant temporal epilepsy aged 2–17 years were operated on from 2011 to 2016, the factors that influenced the outcome of surgical treatment were studied. Favorable prognostic factors for the effectiveness of surgical treatment in the long-term period were: male sex (p<0.01), children older than seven years (p<0.01), disease duration less than three years (p<0.05), intake of fewer than three anticonvulsants drugs (p<0.01), no history of febrile seizures and epileptic reactions (p<0.05), no comorbid conditions (p<0.05), serial seizures and statuses (p<0.01), no early postoperative seizures (p<0.01). The most effective were left-sided resections (p<0.05), lesionectomy (p<0.05) with removal of epileptogenic foci (p<0.01). Thus, rational tactics for surgical treatment of drug-resistant temporal epilepsy in children should be carried out by taking into account the age-related characteristics of the child’s development, the nature of the intercurrent pathology, as well as the alleged etiological factor, taking into account the peculiarity of the course of the pathological process.
AB - Eighty patients with symptomatic drug-resistant temporal epilepsy aged 2–17 years were operated on from 2011 to 2016, the factors that influenced the outcome of surgical treatment were studied. Favorable prognostic factors for the effectiveness of surgical treatment in the long-term period were: male sex (p<0.01), children older than seven years (p<0.01), disease duration less than three years (p<0.05), intake of fewer than three anticonvulsants drugs (p<0.01), no history of febrile seizures and epileptic reactions (p<0.05), no comorbid conditions (p<0.05), serial seizures and statuses (p<0.01), no early postoperative seizures (p<0.01). The most effective were left-sided resections (p<0.05), lesionectomy (p<0.05) with removal of epileptogenic foci (p<0.01). Thus, rational tactics for surgical treatment of drug-resistant temporal epilepsy in children should be carried out by taking into account the age-related characteristics of the child’s development, the nature of the intercurrent pathology, as well as the alleged etiological factor, taking into account the peculiarity of the course of the pathological process.
KW - children
KW - epilepsy
KW - pediatric neurosurgery
KW - personalized medicine
KW - surgery
KW - temporal epilepsy
KW - children
KW - epilepsy
KW - pediatric neurosurgery
KW - personalized medicine
KW - surgery
KW - temporal epilepsy
UR - http://www.scopus.com/inward/record.url?scp=85137220511&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/da623bbd-be77-3f44-91a8-a1ea68b2ef17/
U2 - 10.14300/mnnc.2022.17039
DO - 10.14300/mnnc.2022.17039
M3 - статья
AN - SCOPUS:85137220511
VL - 17
SP - 163
EP - 167
JO - Medical News of North Caucasus
JF - Medical News of North Caucasus
SN - 2073-8137
IS - 2
ER -
ID: 100883016