Endometrial microbiota of women with chronic endometritis and idiopathic infertility › Научные исследования в СПбГУ

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Endometrial microbiota of women with chronic endometritis and idiopathic infertility. / Tapilskaya, Natalya I.; Budilovskaya, Olga V.; Krysanova, Anna A.; Tolibova, Gulrukhsor K.H.; Kopylova, Anastasiya A.; Tsypurdeeva, Natalia D.; Gzgzyan, Alexander M.; Savicheva, Alevtina M.; Kogan, Igor Yu.

в: Akusherstvo i Ginekologiya (Russian Federation), Том 2020, № 4, 2020, стр. 72-81.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Tapilskaya, NI, Budilovskaya, OV, Krysanova, AA, Tolibova, GKH, Kopylova, AA, Tsypurdeeva, ND, Gzgzyan, AM, Savicheva, AM & Kogan, IY 2020, 'Endometrial microbiota of women with chronic endometritis and idiopathic infertility', Akusherstvo i Ginekologiya (Russian Federation), Том. 2020, № 4, стр. 72-81. https://doi.org/10.18565/aig.2020.4.72-81

APA

Tapilskaya, N. I., Budilovskaya, O. V., Krysanova, A. A., Tolibova, G. K. H., Kopylova, A. A., Tsypurdeeva, N. D., Gzgzyan, A. M., Savicheva, A. M., & Kogan, I. Y. (2020). Endometrial microbiota of women with chronic endometritis and idiopathic infertility. Akusherstvo i Ginekologiya (Russian Federation), 2020(4), 72-81. https://doi.org/10.18565/aig.2020.4.72-81

Vancouver

Tapilskaya NI, Budilovskaya OV, Krysanova AA, Tolibova GKH, Kopylova AA, Tsypurdeeva ND и пр. Endometrial microbiota of women with chronic endometritis and idiopathic infertility. Akusherstvo i Ginekologiya (Russian Federation). 2020;2020(4):72-81. https://doi.org/10.18565/aig.2020.4.72-81

Author

Tapilskaya, Natalya I. ; Budilovskaya, Olga V. ; Krysanova, Anna A. ; Tolibova, Gulrukhsor K.H. ; Kopylova, Anastasiya A. ; Tsypurdeeva, Natalia D. ; Gzgzyan, Alexander M. ; Savicheva, Alevtina M. ; Kogan, Igor Yu. / Endometrial microbiota of women with chronic endometritis and idiopathic infertility. в: Akusherstvo i Ginekologiya (Russian Federation). 2020 ; Том 2020, № 4. стр. 72-81.

BibTeX

@article{a7f9081ffaf940ae84819d4e76e78332,

title = "Endometrial microbiota of women with chronic endometritis and idiopathic infertility",

abstract = "Objective. To assess the composition of the microorganisms of the uterine cavity of women with chronic endometritis (CE) and idiopathic infertility. Materials and methods. The study included 145 women of reproductive age with idiopathic infertility. All the patients underwent hysteroscopic examination followed by biopsy histopathological evaluation for immunohistochemical (IHC) and microbiological («Femoflor 16» and «Femoflor Screen» test, DNA-technology, Moscow) studies. Results. According to the results of the IHC study, the CE was detected in 113 (77.9%) patients. The most common microorganisms identified in the uterine cavity were Lactobacilli (66.21%), as well as Staphylococcus (44.83%), Enterobacteriaceae family (22.1%), Ureaplasma spp. (19.3%), Streptococcus spp. (15.2%), Gardnerella vaginalis (11.03%), Atopobium vaginae (10.34%). The presence of Ureaplasma spp. in the uterine cavity significantly increasing the risk of developing CE by 4,5 times (RR=4.483; 95% CI 1.003–20.029). Presence of Atopobium vaginae and Staphylococcus spp. increases the risk of developing pronounced CE by 7 times (RR=6.959; 95% CI 0.856–56.602) and 2.5 times (OS=2.5; 95% CI 1.034–6.043), respectively. Conclusion. The risk of developing CE increases with the persistence of certain microorganisms in the uterine cavity.",

keywords = "Antibiotic therapy, Chronic endometritis, Idiopathic infertility, Immunohistochemistry, Uterine cavity microbiota",

author = "Tapilskaya, {Natalya I.} and Budilovskaya, {Olga V.} and Krysanova, {Anna A.} and Tolibova, {Gulrukhsor K.H.} and Kopylova, {Anastasiya A.} and Tsypurdeeva, {Natalia D.} and Gzgzyan, {Alexander M.} and Savicheva, {Alevtina M.} and Kogan, {Igor Yu}",

year = "2020",

doi = "10.18565/aig.2020.4.72-81",

language = "English",

volume = "2020",

pages = "72--81",

journal = "АКУШЕРСТВО И ГИНЕКОЛОГИЯ",

issn = "0300-9092",

publisher = "Бионика Медиа",

number = "4",

}

RIS

TY - JOUR

T1 - Endometrial microbiota of women with chronic endometritis and idiopathic infertility

AU - Tapilskaya, Natalya I.

AU - Budilovskaya, Olga V.

AU - Krysanova, Anna A.

AU - Tolibova, Gulrukhsor K.H.

AU - Kopylova, Anastasiya A.

AU - Tsypurdeeva, Natalia D.

AU - Gzgzyan, Alexander M.

AU - Savicheva, Alevtina M.

AU - Kogan, Igor Yu

PY - 2020

Y1 - 2020

N2 - Objective. To assess the composition of the microorganisms of the uterine cavity of women with chronic endometritis (CE) and idiopathic infertility. Materials and methods. The study included 145 women of reproductive age with idiopathic infertility. All the patients underwent hysteroscopic examination followed by biopsy histopathological evaluation for immunohistochemical (IHC) and microbiological («Femoflor 16» and «Femoflor Screen» test, DNA-technology, Moscow) studies. Results. According to the results of the IHC study, the CE was detected in 113 (77.9%) patients. The most common microorganisms identified in the uterine cavity were Lactobacilli (66.21%), as well as Staphylococcus (44.83%), Enterobacteriaceae family (22.1%), Ureaplasma spp. (19.3%), Streptococcus spp. (15.2%), Gardnerella vaginalis (11.03%), Atopobium vaginae (10.34%). The presence of Ureaplasma spp. in the uterine cavity significantly increasing the risk of developing CE by 4,5 times (RR=4.483; 95% CI 1.003–20.029). Presence of Atopobium vaginae and Staphylococcus spp. increases the risk of developing pronounced CE by 7 times (RR=6.959; 95% CI 0.856–56.602) and 2.5 times (OS=2.5; 95% CI 1.034–6.043), respectively. Conclusion. The risk of developing CE increases with the persistence of certain microorganisms in the uterine cavity.

AB - Objective. To assess the composition of the microorganisms of the uterine cavity of women with chronic endometritis (CE) and idiopathic infertility. Materials and methods. The study included 145 women of reproductive age with idiopathic infertility. All the patients underwent hysteroscopic examination followed by biopsy histopathological evaluation for immunohistochemical (IHC) and microbiological («Femoflor 16» and «Femoflor Screen» test, DNA-technology, Moscow) studies. Results. According to the results of the IHC study, the CE was detected in 113 (77.9%) patients. The most common microorganisms identified in the uterine cavity were Lactobacilli (66.21%), as well as Staphylococcus (44.83%), Enterobacteriaceae family (22.1%), Ureaplasma spp. (19.3%), Streptococcus spp. (15.2%), Gardnerella vaginalis (11.03%), Atopobium vaginae (10.34%). The presence of Ureaplasma spp. in the uterine cavity significantly increasing the risk of developing CE by 4,5 times (RR=4.483; 95% CI 1.003–20.029). Presence of Atopobium vaginae and Staphylococcus spp. increases the risk of developing pronounced CE by 7 times (RR=6.959; 95% CI 0.856–56.602) and 2.5 times (OS=2.5; 95% CI 1.034–6.043), respectively. Conclusion. The risk of developing CE increases with the persistence of certain microorganisms in the uterine cavity.

KW - Antibiotic therapy

KW - Chronic endometritis

KW - Idiopathic infertility

KW - Immunohistochemistry

KW - Uterine cavity microbiota

UR - http://www.scopus.com/inward/record.url?scp=85085602124&partnerID=8YFLogxK

U2 - 10.18565/aig.2020.4.72-81

DO - 10.18565/aig.2020.4.72-81

M3 - Article

AN - SCOPUS:85085602124

VL - 2020

SP - 72

EP - 81

JO - АКУШЕРСТВО И ГИНЕКОЛОГИЯ

JF - АКУШЕРСТВО И ГИНЕКОЛОГИЯ

SN - 0300-9092

IS - 4

ER -

ID: 76493424