Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Effect of Mn2+ and Ca2+ Ions on Formation of Structurally Ordered Nanoscale Complexes of DNA with Nuclear Proteins HMGB1 and H1. / Chikhirzhina, E. V. ; Osinnikova, D. N. ; Polyanichko, A. M. .
в: Journal of Physics: Conference Series, Том 1695, 012059, 2020.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Effect of Mn2+ and Ca2+ Ions on Formation of Structurally Ordered Nanoscale Complexes of DNA with Nuclear Proteins HMGB1 and H1
AU - Chikhirzhina, E. V.
AU - Osinnikova, D. N.
AU - Polyanichko, A. M.
PY - 2020
Y1 - 2020
N2 - The structural organization of DNA in complex with linker histone H1 and non-histone chromosomal protein HMGB1 in presence of calcium and manganese ions have been studied using FTIR and UV circular dichroism spectroscopy. We have demonstrated that the presence of calcium ions leads to the formation of highly ordered DNA-H1-HMGB1 structures, while manganese ions decrease the order in the earlier reported nanoscale complexes.
AB - The structural organization of DNA in complex with linker histone H1 and non-histone chromosomal protein HMGB1 in presence of calcium and manganese ions have been studied using FTIR and UV circular dichroism spectroscopy. We have demonstrated that the presence of calcium ions leads to the formation of highly ordered DNA-H1-HMGB1 structures, while manganese ions decrease the order in the earlier reported nanoscale complexes.
U2 - 10.1088/1742-6596/1695/1/012059
DO - 10.1088/1742-6596/1695/1/012059
M3 - Article
VL - 1695
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
M1 - 012059
ER -
ID: 72125718