Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
E-cadherin as a novel surface marker of spermatogonial stem cells. / Tolkunova, E. N.; Malashicheva, A. B.; Chikhirzhina, E. V.; Kostyleva, E. I.; Zeng, W.; Luo, J.; Dobrinski, I.; Hierholzer, A.; Kemler, R.; Tomilin, A. N.
в: Cell and Tissue Biology, Том 3, № 2, 22.05.2009, стр. 103-109.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - E-cadherin as a novel surface marker of spermatogonial stem cells
AU - Tolkunova, E. N.
AU - Malashicheva, A. B.
AU - Chikhirzhina, E. V.
AU - Kostyleva, E. I.
AU - Zeng, W.
AU - Luo, J.
AU - Dobrinski, I.
AU - Hierholzer, A.
AU - Kemler, R.
AU - Tomilin, A. N.
PY - 2009/5/22
Y1 - 2009/5/22
N2 - Spermatogenesis is a fundamental biological process that ensures the transition of a gene from one ganeration to another via male gametes. This process relies on a rare population of testicular cells called spermatogonial stem cells (SSCs), which self-renew throughout adult male life and differentiate into mature gametes. Despite the longstanding study of SSCs, their biological properties remain largely unknown, which is partly due to the very limited availability of these cells. Here, we show that cell adhesion protein E-cadherin is a highly specific surface marker of mouse SSCs that can be successfully used to enrich them.
AB - Spermatogenesis is a fundamental biological process that ensures the transition of a gene from one ganeration to another via male gametes. This process relies on a rare population of testicular cells called spermatogonial stem cells (SSCs), which self-renew throughout adult male life and differentiate into mature gametes. Despite the longstanding study of SSCs, their biological properties remain largely unknown, which is partly due to the very limited availability of these cells. Here, we show that cell adhesion protein E-cadherin is a highly specific surface marker of mouse SSCs that can be successfully used to enrich them.
KW - E-cadherin
KW - Spermatogenesis
KW - Spermatogonial stem cells
UR - http://www.scopus.com/inward/record.url?scp=65649153374&partnerID=8YFLogxK
U2 - 10.1134/S1990519X09020011
DO - 10.1134/S1990519X09020011
M3 - Article
VL - 3
SP - 103
EP - 109
JO - Cell and Tissue Biology
JF - Cell and Tissue Biology
SN - 1990-519X
IS - 2
ER -
ID: 5318893