TY - JOUR

T1 - Dynamic properties of adsorption layers of pulmonary surfactants. Influence of matter exchange with bulk phase

AU - Bykov, A.G.

AU - Milyaeva, O.Yu.

AU - Isakov, N.A.

AU - Michailov, A.V.

AU - Loglio, G.

AU - Miller, R.

AU - Noskov, B.A.

N1 - Funding Information: The reported study was funded by RFBR , project number 20-33-70056. The authors are grateful to the Center of Thermal Analysis and Calorimetry of St. Petersburg State University for the assistance in the investigation of the surface layer morphology. Publisher Copyright: © 2020 Elsevier B.V. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/2/20

Y1 - 2021/2/20

N2 - The dynamic surface properties of solutions of pulmonary surfactant (PS) were investigated at various temperatures and in a broad range of surface tensions. The efficient dynamic surface elasticity was determined for the first time in case when the characteristic adsorption time is comparable with the period of surface area oscillations. The mechanical relaxation in the PS adsorption layer is accelerated strongly not only in the course of compression, but also in the course of expansion due to the formation of a sublayer. The harmonic oscillations of the surface area induce stationary oscillations of the surface tension if the characteristic adsorption time does not exceed the oscillation period and the sublayer formation is sufficiently fast. The information on the dynamic properties of the PS adsorption layer allows estimation of the PS efficiency in medical applications.

AB - The dynamic surface properties of solutions of pulmonary surfactant (PS) were investigated at various temperatures and in a broad range of surface tensions. The efficient dynamic surface elasticity was determined for the first time in case when the characteristic adsorption time is comparable with the period of surface area oscillations. The mechanical relaxation in the PS adsorption layer is accelerated strongly not only in the course of compression, but also in the course of expansion due to the formation of a sublayer. The harmonic oscillations of the surface area induce stationary oscillations of the surface tension if the characteristic adsorption time does not exceed the oscillation period and the sublayer formation is sufficiently fast. The information on the dynamic properties of the PS adsorption layer allows estimation of the PS efficiency in medical applications.

KW - поверхностная упругость, нелинейное поведение, легочные ПАВ

KW - surface elasticity

KW - Non-linear behavior

KW - Pulmonary surfactants

KW - adsorption kinetics

KW - Adsorption kinetic

KW - Surface elasticity

KW - LUNG SURFACTANT

KW - COMPRESSION

KW - MONOLAYERS

KW - PEPTIDE

KW - ELASTICITY

KW - ATOMIC-FORCE MICROSCOPY

KW - FILMS

KW - SP-C

KW - HYDROPHOBIC SURFACTANT

KW - PROTEINS SP-B

UR - http://www.scopus.com/inward/record.url?scp=85095826626&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/105f8984-cedb-39e8-9767-3ea73602c8ed/

U2 - 10.1016/j.colsurfa.2020.125851

DO - 10.1016/j.colsurfa.2020.125851

M3 - Article

AN - SCOPUS:85095826626

VL - 611

JO - Colloids and Surfaces A: Physicochemical and Engineering Aspects

JF - Colloids and Surfaces A: Physicochemical and Engineering Aspects

SN - 0927-7757

M1 - 125851

ER -