Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
DNA-polymer complexes for gene therapy. / Kasyanenko, N. A.; Lysyakova, L. A.; Dribinskii, B. A.; Zolotova, Yu I.; Nazarova, O. V.; Panarin, E. F.
в: Polymer Science - Series C, Том 54, № 1, 09.2012, стр. 57-68.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - DNA-polymer complexes for gene therapy
AU - Kasyanenko, N. A.
AU - Lysyakova, L. A.
AU - Dribinskii, B. A.
AU - Zolotova, Yu I.
AU - Nazarova, O. V.
AU - Panarin, E. F.
N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/9
Y1 - 2012/9
N2 - The condensation of DNA induced by vinyl saccharide graft copolymers of N-methacryloy-lamino-D-glucose with N,N-dimethylaminoethyl methacrylate and N-vinylpyrrolidone with N-vinylamine and induced by the linear polycation poly(L-lysine) in solution, as well as the conformational changes of a DNA molecule during its interaction with polycations in solution, is studied by atomic-force microscopy, low-gradient viscometry, dynamic birefringence, spectrophotometry, circular dichroism, and electrophoresis. The differences in the conformational changes of DNA related to the effect of polycations and other agents inducing its condensation are discussed.
AB - The condensation of DNA induced by vinyl saccharide graft copolymers of N-methacryloy-lamino-D-glucose with N,N-dimethylaminoethyl methacrylate and N-vinylpyrrolidone with N-vinylamine and induced by the linear polycation poly(L-lysine) in solution, as well as the conformational changes of a DNA molecule during its interaction with polycations in solution, is studied by atomic-force microscopy, low-gradient viscometry, dynamic birefringence, spectrophotometry, circular dichroism, and electrophoresis. The differences in the conformational changes of DNA related to the effect of polycations and other agents inducing its condensation are discussed.
KW - CONFORMATIONAL TRANSITIONS
KW - COMPACT FORM
KW - CONDENSATION
KW - DELIVERY
KW - IONS
KW - TRANSFECTION
KW - COPOLYMERS
KW - VECTORS
KW - CATIONS
KW - ETHANOL
UR - http://www.scopus.com/inward/record.url?scp=84866037369&partnerID=8YFLogxK
U2 - 10.1134/S181123821207003X
DO - 10.1134/S181123821207003X
M3 - Article
VL - 54
SP - 57
EP - 68
JO - Polymer Science - Series C
JF - Polymer Science - Series C
SN - 1811-2382
IS - 1
ER -
ID: 5347501