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Disturbance in mammalian cognition caused by accumulation of silver in brain. / Antsiferova, Anna A.; Kopaeva, Marina Yu; Kochkin, Vyacheslav N.; Kashkarov, Pavel K.; Kovalchuk, Mikhail V.

в: Toxics, Том 9, № 2, 30, 02.2021, стр. 1-13.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Antsiferova, AA, Kopaeva, MY, Kochkin, VN, Kashkarov, PK & Kovalchuk, MV 2021, 'Disturbance in mammalian cognition caused by accumulation of silver in brain', Toxics, Том. 9, № 2, 30, стр. 1-13. https://doi.org/10.3390/toxics9020030

APA

Antsiferova, A. A., Kopaeva, M. Y., Kochkin, V. N., Kashkarov, P. K., & Kovalchuk, M. V. (2021). Disturbance in mammalian cognition caused by accumulation of silver in brain. Toxics, 9(2), 1-13. [30]. https://doi.org/10.3390/toxics9020030

Vancouver

Antsiferova AA, Kopaeva MY, Kochkin VN, Kashkarov PK, Kovalchuk MV. Disturbance in mammalian cognition caused by accumulation of silver in brain. Toxics. 2021 Февр.;9(2):1-13. 30. https://doi.org/10.3390/toxics9020030

Author

Antsiferova, Anna A. ; Kopaeva, Marina Yu ; Kochkin, Vyacheslav N. ; Kashkarov, Pavel K. ; Kovalchuk, Mikhail V. / Disturbance in mammalian cognition caused by accumulation of silver in brain. в: Toxics. 2021 ; Том 9, № 2. стр. 1-13.

BibTeX

@article{79c89dfac1114b71bbd0df2f35002f0b,
title = "Disturbance in mammalian cognition caused by accumulation of silver in brain",
abstract = "The influence of daily prolonged administration of silver nanoparticles on the cognitive functions of a model mammal was studied. The accumulation of silver in the whole brain and the hippocampus, cerebellum, cortex and residual brain tissue of the mouse was investigated by highly precise and representative neutron activation analysis, and histological studies were conducted. Here, we show that long-term memory impairments were caused by the accumulation of silver nanoparticles in the brain and its subregions, such as the hippocampus, cerebellum and cortex, in a step-like manner by disturbance of hippocampal cell integrity. Three different approaches allowed us to observe this phenomenon and discover the reasons it occurred.",
keywords = "Accumulation in brain, Biodistribution, CA2, Cerebellum, Contextual memory, Cortex, Fear, Hip-pocampus, Neutron activation analysis, Silver nanoparticles",
author = "Antsiferova, {Anna A.} and Kopaeva, {Marina Yu} and Kochkin, {Vyacheslav N.} and Kashkarov, {Pavel K.} and Kovalchuk, {Mikhail V.}",
note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
month = feb,
doi = "10.3390/toxics9020030",
language = "English",
volume = "9",
pages = "1--13",
journal = "Toxics",
issn = "2305-6304",
publisher = "MDPI AG",
number = "2",

}

RIS

TY - JOUR

T1 - Disturbance in mammalian cognition caused by accumulation of silver in brain

AU - Antsiferova, Anna A.

AU - Kopaeva, Marina Yu

AU - Kochkin, Vyacheslav N.

AU - Kashkarov, Pavel K.

AU - Kovalchuk, Mikhail V.

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/2

Y1 - 2021/2

N2 - The influence of daily prolonged administration of silver nanoparticles on the cognitive functions of a model mammal was studied. The accumulation of silver in the whole brain and the hippocampus, cerebellum, cortex and residual brain tissue of the mouse was investigated by highly precise and representative neutron activation analysis, and histological studies were conducted. Here, we show that long-term memory impairments were caused by the accumulation of silver nanoparticles in the brain and its subregions, such as the hippocampus, cerebellum and cortex, in a step-like manner by disturbance of hippocampal cell integrity. Three different approaches allowed us to observe this phenomenon and discover the reasons it occurred.

AB - The influence of daily prolonged administration of silver nanoparticles on the cognitive functions of a model mammal was studied. The accumulation of silver in the whole brain and the hippocampus, cerebellum, cortex and residual brain tissue of the mouse was investigated by highly precise and representative neutron activation analysis, and histological studies were conducted. Here, we show that long-term memory impairments were caused by the accumulation of silver nanoparticles in the brain and its subregions, such as the hippocampus, cerebellum and cortex, in a step-like manner by disturbance of hippocampal cell integrity. Three different approaches allowed us to observe this phenomenon and discover the reasons it occurred.

KW - Accumulation in brain

KW - Biodistribution

KW - CA2

KW - Cerebellum

KW - Contextual memory

KW - Cortex

KW - Fear

KW - Hip-pocampus

KW - Neutron activation analysis

KW - Silver nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=85100612993&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ed1f6a88-a8b8-3ada-862d-f55b2e7f78bd/

U2 - 10.3390/toxics9020030

DO - 10.3390/toxics9020030

M3 - Article

AN - SCOPUS:85100612993

VL - 9

SP - 1

EP - 13

JO - Toxics

JF - Toxics

SN - 2305-6304

IS - 2

M1 - 30

ER -

ID: 88196123