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Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions. / Morris, K.M.; Kirby, K.; Beatty, J.A.; Barrs, V.R.; Cattley, S.; David, V.; O'Brien, S.J.; Menotti-Raymond, M.; Belov, K.

в: Journal of Heredity, № 4, 2014, стр. 493-505.

Результаты исследований: Научные публикации в периодических изданияхстатья

Harvard

Morris, KM, Kirby, K, Beatty, JA, Barrs, VR, Cattley, S, David, V, O'Brien, SJ, Menotti-Raymond, M & Belov, K 2014, 'Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions', Journal of Heredity, № 4, стр. 493-505. https://doi.org/10.1093/jhered/esu017

APA

Morris, K. M., Kirby, K., Beatty, J. A., Barrs, V. R., Cattley, S., David, V., O'Brien, S. J., Menotti-Raymond, M., & Belov, K. (2014). Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions. Journal of Heredity, (4), 493-505. https://doi.org/10.1093/jhered/esu017

Vancouver

Author

Morris, K.M. ; Kirby, K. ; Beatty, J.A. ; Barrs, V.R. ; Cattley, S. ; David, V. ; O'Brien, S.J. ; Menotti-Raymond, M. ; Belov, K. / Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions. в: Journal of Heredity. 2014 ; № 4. стр. 493-505.

BibTeX

@article{bb00409cfa314aaeacc2c8599ec5bd28,
title = "Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions",
abstract = "Diversity within the major histocompatibility complex (MHC) reflects the immunological fitness of a population. MHC-linked microsatellite markers provide a simple and an inexpensive method for studying MHC diversity in large-scale studies. We have developed 6 MHC-linked microsatellite markers in the domestic cat and used these, in conjunction with 5 neutral microsatellites, to assess MHC diversity in domestic mixed breed (n = 129) and purebred Burmese (n = 61) cat populations in Australia. The MHC of outbred Australian cats is polymorphic (average allelic richness = 8.52), whereas the Burmese population has significantly lower MHC diversity (average allelic richness = 6.81; P <0.01). The MHC-linked microsatellites along with MHC cloning and sequencing demonstrated moderate MHC diversity in cheetahs (n = 13) and extremely low diversity in Gir lions (n = 13). Our MHC-linked microsatellite markers have potential future use in diversity and disease studies in other populations and breeds of cats as well as in wi",
author = "K.M. Morris and K. Kirby and J.A. Beatty and V.R. Barrs and S. Cattley and V. David and S.J. O'Brien and M. Menotti-Raymond and K. Belov",
year = "2014",
doi = "10.1093/jhered/esu017",
language = "English",
pages = "493--505",
journal = "Journal of Heredity",
issn = "0022-1503",
publisher = "Oxford University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs, and gir lions

AU - Morris, K.M.

AU - Kirby, K.

AU - Beatty, J.A.

AU - Barrs, V.R.

AU - Cattley, S.

AU - David, V.

AU - O'Brien, S.J.

AU - Menotti-Raymond, M.

AU - Belov, K.

PY - 2014

Y1 - 2014

N2 - Diversity within the major histocompatibility complex (MHC) reflects the immunological fitness of a population. MHC-linked microsatellite markers provide a simple and an inexpensive method for studying MHC diversity in large-scale studies. We have developed 6 MHC-linked microsatellite markers in the domestic cat and used these, in conjunction with 5 neutral microsatellites, to assess MHC diversity in domestic mixed breed (n = 129) and purebred Burmese (n = 61) cat populations in Australia. The MHC of outbred Australian cats is polymorphic (average allelic richness = 8.52), whereas the Burmese population has significantly lower MHC diversity (average allelic richness = 6.81; P <0.01). The MHC-linked microsatellites along with MHC cloning and sequencing demonstrated moderate MHC diversity in cheetahs (n = 13) and extremely low diversity in Gir lions (n = 13). Our MHC-linked microsatellite markers have potential future use in diversity and disease studies in other populations and breeds of cats as well as in wi

AB - Diversity within the major histocompatibility complex (MHC) reflects the immunological fitness of a population. MHC-linked microsatellite markers provide a simple and an inexpensive method for studying MHC diversity in large-scale studies. We have developed 6 MHC-linked microsatellite markers in the domestic cat and used these, in conjunction with 5 neutral microsatellites, to assess MHC diversity in domestic mixed breed (n = 129) and purebred Burmese (n = 61) cat populations in Australia. The MHC of outbred Australian cats is polymorphic (average allelic richness = 8.52), whereas the Burmese population has significantly lower MHC diversity (average allelic richness = 6.81; P <0.01). The MHC-linked microsatellites along with MHC cloning and sequencing demonstrated moderate MHC diversity in cheetahs (n = 13) and extremely low diversity in Gir lions (n = 13). Our MHC-linked microsatellite markers have potential future use in diversity and disease studies in other populations and breeds of cats as well as in wi

U2 - 10.1093/jhered/esu017

DO - 10.1093/jhered/esu017

M3 - Article

SP - 493

EP - 505

JO - Journal of Heredity

JF - Journal of Heredity

SN - 0022-1503

IS - 4

ER -

ID: 7066134