Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Cyclocondensation of 2-fluoro-5-nitrobenzaldehyde with amidines. New synthesis of isoquinolines. / Dar'in, D. V.; Selivanov, S. I.; Lobanov, P. S.; Potekhin, A. A.
в: Chemistry of Heterocyclic Compounds, Том 40, № 7, 01.07.2004, стр. 888-894.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Cyclocondensation of 2-fluoro-5-nitrobenzaldehyde with amidines. New synthesis of isoquinolines
AU - Dar'in, D. V.
AU - Selivanov, S. I.
AU - Lobanov, P. S.
AU - Potekhin, A. A.
PY - 2004/7/1
Y1 - 2004/7/1
N2 - The direction of the cyclocondensation of 2-fluoro-5-nitrobenzaldehyde with five amidines having α-hydrogen atoms has been studied. It was established that depending on the structure of the amidine the main products of the reaction may be not only quinazolines but also 3-aminoisoquinolines. A new convenient route has been found for the synthesis of 3-aminoisoquinolines consisting of the cyclocondensation of α-acylacetamidines with 2-fluoro-5-nitrobenzaldehyde.
AB - The direction of the cyclocondensation of 2-fluoro-5-nitrobenzaldehyde with five amidines having α-hydrogen atoms has been studied. It was established that depending on the structure of the amidine the main products of the reaction may be not only quinazolines but also 3-aminoisoquinolines. A new convenient route has been found for the synthesis of 3-aminoisoquinolines consisting of the cyclocondensation of α-acylacetamidines with 2-fluoro-5-nitrobenzaldehyde.
KW - 2-fluoro-5- nitrobenzaldehyde
KW - amidines as N,N- and C,N-dinucleophiles
KW - cyclocondensation
KW - isoquinolines
UR - http://www.scopus.com/inward/record.url?scp=6344263398&partnerID=8YFLogxK
U2 - 10.1023/B:COHC.0000044571.89322.4e
DO - 10.1023/B:COHC.0000044571.89322.4e
M3 - Article
AN - SCOPUS:6344263398
VL - 40
SP - 888
EP - 894
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 7
ER -
ID: 36262537