TY - JOUR

T1 - Cyclization of ortho-ethynylbiaryls as an emerging versatile tool for the construction of polycyclic arenes

AU - Pankova, Alena S.

AU - Shestakov, Aleksandr N.

AU - Kuznetsov, Mikhail A.

N1 - Обзор

PY - 2019

Y1 - 2019

N2 - Cyclization and cycloisomerization of ortho-aryl(ethynyl)arenes provide an easy direct access to fused polycyclic aromatic carbo- A nd heterocycles. This methodology has demonstrated an impressive progress in the recent years. The goal of this review is to give a comprehensive outlook on the synthetic potential, scope, limitations, and mechanistic aspects of the cyclization reactions. The material is arranged according to the activation method that can be used to induce cyclization: Pyrolysis, metal catalysis, electrophilic activation, radical induction, base catalysis. Particular attention is paid to the specificity of ortho-ethynylbiaryls with a heterocyclic central core.

AB - Cyclization and cycloisomerization of ortho-aryl(ethynyl)arenes provide an easy direct access to fused polycyclic aromatic carbo- A nd heterocycles. This methodology has demonstrated an impressive progress in the recent years. The goal of this review is to give a comprehensive outlook on the synthetic potential, scope, limitations, and mechanistic aspects of the cyclization reactions. The material is arranged according to the activation method that can be used to induce cyclization: Pyrolysis, metal catalysis, electrophilic activation, radical induction, base catalysis. Particular attention is paid to the specificity of ortho-ethynylbiaryls with a heterocyclic central core.

KW - циклизация

UR - http://www.scopus.com/inward/record.url?scp=85069608110&partnerID=8YFLogxK

U2 - 10.1070/RCR4855

DO - 10.1070/RCR4855

M3 - Article

AN - SCOPUS:85069608110

VL - 88

SP - 594

EP - 643

JO - Russian Chemical Reviews

JF - Russian Chemical Reviews

SN - 0036-021X

IS - 6

ER -