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Cyclic diazo compounds in the construction of spirocyclic scaffolds. / Solovyev, Igor; Eremeyeva, Maria; Zhukovsky, Daniil; Dar'in, Dmitry; Krasavin, Mikhail.

в: Tetrahedron Letters, 2020.

Результаты исследований: Научные публикации в периодических изданияхОбзорная статьяРецензирование

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@article{4c50be4a721643ef91795f784dd549c8,
title = "Cyclic diazo compounds in the construction of spirocyclic scaffolds",
abstract = "Spirocycles represent an emerging class of privileged motifs for drug discovery. The versatility of diazo compounds in constructing cyclic frameworks in general makes cyclic diazo compounds a potentially highly prolific source of spirocyclic scaffolds. While the first examples of obtaining a spirocycle from a cyclic diazo compound are dated as far back as 42 years ago, there appears to be a resurgence of novel methodologies based on this premise. The present Digest Article aims to cover the literature on the subject to-date.",
keywords = "Cyclization, Diazo compounds, Multiple reactivity modes, Privileged structures for drug discovery, Spirocyclic scaffolds",
author = "Igor Solovyev and Maria Eremeyeva and Daniil Zhukovsky and Dmitry Dar'in and Mikhail Krasavin",
note = "Funding Information: This work was supported by the Russian Foundation for Basic Research (project grant 19-03-00775 ). Igor Solovyev is grateful to the Russian Foundation for Basic Research for his graduate student fellowship (project grant 19-33-90018). Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
doi = "10.1016/j.tetlet.2020.152671",
language = "English",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Cyclic diazo compounds in the construction of spirocyclic scaffolds

AU - Solovyev, Igor

AU - Eremeyeva, Maria

AU - Zhukovsky, Daniil

AU - Dar'in, Dmitry

AU - Krasavin, Mikhail

N1 - Funding Information: This work was supported by the Russian Foundation for Basic Research (project grant 19-03-00775 ). Igor Solovyev is grateful to the Russian Foundation for Basic Research for his graduate student fellowship (project grant 19-33-90018). Publisher Copyright: © 2020 Elsevier Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020

Y1 - 2020

N2 - Spirocycles represent an emerging class of privileged motifs for drug discovery. The versatility of diazo compounds in constructing cyclic frameworks in general makes cyclic diazo compounds a potentially highly prolific source of spirocyclic scaffolds. While the first examples of obtaining a spirocycle from a cyclic diazo compound are dated as far back as 42 years ago, there appears to be a resurgence of novel methodologies based on this premise. The present Digest Article aims to cover the literature on the subject to-date.

AB - Spirocycles represent an emerging class of privileged motifs for drug discovery. The versatility of diazo compounds in constructing cyclic frameworks in general makes cyclic diazo compounds a potentially highly prolific source of spirocyclic scaffolds. While the first examples of obtaining a spirocycle from a cyclic diazo compound are dated as far back as 42 years ago, there appears to be a resurgence of novel methodologies based on this premise. The present Digest Article aims to cover the literature on the subject to-date.

KW - Cyclization

KW - Diazo compounds

KW - Multiple reactivity modes

KW - Privileged structures for drug discovery

KW - Spirocyclic scaffolds

UR - http://www.scopus.com/inward/record.url?scp=85097458338&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/1f42eda9-f987-33f1-a157-66065eabb140/

U2 - 10.1016/j.tetlet.2020.152671

DO - 10.1016/j.tetlet.2020.152671

M3 - Review article

AN - SCOPUS:85097458338

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

M1 - 152671

ER -

ID: 71835592