Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Conserved noncoding sequences highlight shared components of regulatory networks in dicotyledonous plants. / Baxter, Laura; Jironkin, Aleksey; Hickman, Richard; Moore, Jay; Barrington, Christopher; Krusche, Peter; Dyer, Nigel P.; Buchanan-Wollaston, Vicky; Tiskin, Alexander; Beynon, Jim; Denby, Katherine; Ott, Sascha.
в: Plant Cell, Том 24, № 10, 01.01.2012, стр. 3949-3965.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Conserved noncoding sequences highlight shared components of regulatory networks in dicotyledonous plants
AU - Baxter, Laura
AU - Jironkin, Aleksey
AU - Hickman, Richard
AU - Moore, Jay
AU - Barrington, Christopher
AU - Krusche, Peter
AU - Dyer, Nigel P.
AU - Buchanan-Wollaston, Vicky
AU - Tiskin, Alexander
AU - Beynon, Jim
AU - Denby, Katherine
AU - Ott, Sascha
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Conserved noncoding sequences (CNSs) in DNA are reliable pointers to regulatory elements controlling gene expression. Using a comparative genomics approach with four dicotyledonous plant species (Arabidopsis thaliana, papaya [Carica papaya], poplar [Populus trichocarpa], and grape [Vitis vinifera]), we detected hundreds of CNSs upstream of Arabidopsis genes. Distinct positioning, length, and enrichment for transcription factor binding sites suggest these CNSs play a functional role in transcriptional regulation. The enrichment of transcription factors within the set of genes associated with CNS is consistent with the hypothesis that together they form part of a conserved transcriptional network whose function is to regulate other transcription factors and control development. We identified a set of promoters where regulatory mechanisms are likely to be shared between the model organism Arabidopsis and other dicots, providing areas of focus for further research. © 2012 American Society of Plant Biologists. All rights reserved.
AB - Conserved noncoding sequences (CNSs) in DNA are reliable pointers to regulatory elements controlling gene expression. Using a comparative genomics approach with four dicotyledonous plant species (Arabidopsis thaliana, papaya [Carica papaya], poplar [Populus trichocarpa], and grape [Vitis vinifera]), we detected hundreds of CNSs upstream of Arabidopsis genes. Distinct positioning, length, and enrichment for transcription factor binding sites suggest these CNSs play a functional role in transcriptional regulation. The enrichment of transcription factors within the set of genes associated with CNS is consistent with the hypothesis that together they form part of a conserved transcriptional network whose function is to regulate other transcription factors and control development. We identified a set of promoters where regulatory mechanisms are likely to be shared between the model organism Arabidopsis and other dicots, providing areas of focus for further research. © 2012 American Society of Plant Biologists. All rights reserved.
UR - http://www.scopus.com/inward/record.url?scp=84870664380&partnerID=8YFLogxK
U2 - 10.1105/tpc.112.103010
DO - 10.1105/tpc.112.103010
M3 - Article
C2 - 23110901
AN - SCOPUS:84870664380
VL - 24
SP - 3949
EP - 3965
JO - Plant Cell
JF - Plant Cell
SN - 1040-4651
IS - 10
ER -
ID: 127708242