Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Comparison of adjuvanticity and autoantibody inducing capacity of endotoxin and radio-detoxified endotoxin in mice. / Klimovich, V. B.; Samoilovich, M. P.; Denisova, G. N.; Sirota, N. S.; Schuls, T. S.; Zeludov, V. I.; Bertók, L.
в: Acta Microbiologica Hungarica, Том 33, № 4, 1986, стр. 311-315.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Comparison of adjuvanticity and autoantibody inducing capacity of endotoxin and radio-detoxified endotoxin in mice.
AU - Klimovich, V. B.
AU - Samoilovich, M. P.
AU - Denisova, G. N.
AU - Sirota, N. S.
AU - Schuls, T. S.
AU - Zeludov, V. I.
AU - Bertók, L.
PY - 1986
Y1 - 1986
N2 - Endotoxin (LPS) and radio-detoxified endotoxin (RD-LPS: 150 kGy 60Co-gamma irradiated) preparations were compared in mice (C57Bl X CBA: F1/Rapo) for capacity to enhance the immune response against sheep red blood cells and to induce the production of antibody against autologous (bromelain-treated) erythrocytes. As RD-LPS retains its capacity to stimulate immune response against heterologous antigen, it may be used as an immuno-adjuvant. The LPS preparation gave rise to a significant increase of autoreactive cells. However, RD-LPS activated the autoantibody forming cells only to a very small degree.
AB - Endotoxin (LPS) and radio-detoxified endotoxin (RD-LPS: 150 kGy 60Co-gamma irradiated) preparations were compared in mice (C57Bl X CBA: F1/Rapo) for capacity to enhance the immune response against sheep red blood cells and to induce the production of antibody against autologous (bromelain-treated) erythrocytes. As RD-LPS retains its capacity to stimulate immune response against heterologous antigen, it may be used as an immuno-adjuvant. The LPS preparation gave rise to a significant increase of autoreactive cells. However, RD-LPS activated the autoantibody forming cells only to a very small degree.
UR - http://www.scopus.com/inward/record.url?scp=0022839440&partnerID=8YFLogxK
M3 - Article
C2 - 3307274
AN - SCOPUS:0022839440
VL - 33
SP - 311
EP - 315
JO - Acta Microbiologica et Immunologica Hungarica
JF - Acta Microbiologica et Immunologica Hungarica
SN - 1217-8950
IS - 4
ER -
ID: 89781960