Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Comparing laser vs mechanical lithotripsy in suction mini‐PCNL for kidney stone disease: A prospective multicentre study by the endourology section of EAU. / Cormio, Angelo; Gauhar, Vineet; Somani, Bhaskar K.; Kalathia, Jaisukh; Gadzhiev, Nariman; Zawadzki, Marek; Laymon, Mahmoud; Tan, Karl; Tak, Gopal Ramdas; Tokas, Theodoros; Agrawal, Madhu Sudan; De La Rosette, Jean; Petkova, Kremena; Taguchi, Kazumi; Gorelov, Dmitriy; Martov, Alexey G.; Lopes, Leonardo Gomes; Gökce, Mehmet Ilker; Kamal, Wissam; Ferretti, Stefania; Desai, Devang; Shwani, Yadgar Abduljabbar; Fong, Khi Yung; Yuen, Steffi Kar Kei; Skolarikos, Andreas; Cepeda, Marcos; Herrmann, Thomas R. W.; Castellani, Daniele.
в: BJUI Compass, Том 6, № 10, e70075, 01.10.2025.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Comparing laser vs mechanical lithotripsy in suction mini‐PCNL for kidney stone disease: A prospective multicentre study by the endourology section of EAU
AU - Cormio, Angelo
AU - Gauhar, Vineet
AU - Somani, Bhaskar K.
AU - Kalathia, Jaisukh
AU - Gadzhiev, Nariman
AU - Zawadzki, Marek
AU - Laymon, Mahmoud
AU - Tan, Karl
AU - Tak, Gopal Ramdas
AU - Tokas, Theodoros
AU - Agrawal, Madhu Sudan
AU - De La Rosette, Jean
AU - Petkova, Kremena
AU - Taguchi, Kazumi
AU - Gorelov, Dmitriy
AU - Martov, Alexey G.
AU - Lopes, Leonardo Gomes
AU - Gökce, Mehmet Ilker
AU - Kamal, Wissam
AU - Ferretti, Stefania
AU - Desai, Devang
AU - Shwani, Yadgar Abduljabbar
AU - Fong, Khi Yung
AU - Yuen, Steffi Kar Kei
AU - Skolarikos, Andreas
AU - Cepeda, Marcos
AU - Herrmann, Thomas R. W.
AU - Castellani, Daniele
PY - 2025/10/1
Y1 - 2025/10/1
N2 - OBJECTIVES: To compare perioperative outcomes, complications and stone-free rates (SFRs) between laser and non-laser lithotripsy in suction-assisted mini-PCNL (SM-PCNL).SUBJECTS AND METHODS: This prospective multicentre study enrolled adults with normal kidneys undergoing SM-PCNL (14-22 Fr) across 30 international centres (March-November 2024). Patients were divided into laser (Group 1) and non-laser (Group 2) groups. Propensity score matching (2:1) was performed based on age, sex, Guy's score and patient position. Primary outcomes were complications and 30-day SFR assessed by CT. Multivariable logistic regression identified predictors of complete stone clearance and complications.RESULTS: After matching, 748 patients were analysed (Group 1: 448; Group 2: 300). Non-laser devices were associated with shorter lithotripsy (12 vs 18 min, p < 0.001) and operative times (37 vs 45 min, p < 0.001) and higher SFR (intraoperative: 91.3% vs 80.7%; 30-day: 87.7% vs 82.1%). However, transfusions (3.3% vs 0.2%), pelvic perforation and pleural injury (each 3.0%) were more common in Group 2. On multivariable analysis, single-step dilation (OR 3.05) and sheath sizes of 16.5-18 Fr (OR 1.98) or 20-22 Fr (OR 2.72) were associated with higher odds of stone-free status, while skin-to-stone distance >8 cm (OR 0.5) and combined fluoroscopy/ultrasound access (0.28) reduced this likelihood. Stone volume (OR 1.03), serial dilation with non-metal dilators (OR 2.64) and combined fluoroscopy/ultrasound access (OR 2.11) were factors associated with higher odds of complications. The lithotripsy technology had no direct bearing on complications.CONCLUSIONS: Both laser and non-laser lithotripsy are effective in SM-PCNL. Non-laser devices improve efficiency and lasers were preferentially used with 14-18 fr access tracts.
AB - OBJECTIVES: To compare perioperative outcomes, complications and stone-free rates (SFRs) between laser and non-laser lithotripsy in suction-assisted mini-PCNL (SM-PCNL).SUBJECTS AND METHODS: This prospective multicentre study enrolled adults with normal kidneys undergoing SM-PCNL (14-22 Fr) across 30 international centres (March-November 2024). Patients were divided into laser (Group 1) and non-laser (Group 2) groups. Propensity score matching (2:1) was performed based on age, sex, Guy's score and patient position. Primary outcomes were complications and 30-day SFR assessed by CT. Multivariable logistic regression identified predictors of complete stone clearance and complications.RESULTS: After matching, 748 patients were analysed (Group 1: 448; Group 2: 300). Non-laser devices were associated with shorter lithotripsy (12 vs 18 min, p < 0.001) and operative times (37 vs 45 min, p < 0.001) and higher SFR (intraoperative: 91.3% vs 80.7%; 30-day: 87.7% vs 82.1%). However, transfusions (3.3% vs 0.2%), pelvic perforation and pleural injury (each 3.0%) were more common in Group 2. On multivariable analysis, single-step dilation (OR 3.05) and sheath sizes of 16.5-18 Fr (OR 1.98) or 20-22 Fr (OR 2.72) were associated with higher odds of stone-free status, while skin-to-stone distance >8 cm (OR 0.5) and combined fluoroscopy/ultrasound access (0.28) reduced this likelihood. Stone volume (OR 1.03), serial dilation with non-metal dilators (OR 2.64) and combined fluoroscopy/ultrasound access (OR 2.11) were factors associated with higher odds of complications. The lithotripsy technology had no direct bearing on complications.CONCLUSIONS: Both laser and non-laser lithotripsy are effective in SM-PCNL. Non-laser devices improve efficiency and lasers were preferentially used with 14-18 fr access tracts.
KW - Kidney calculi
KW - Laser
KW - Percutaneous nephrolithotomy
KW - Sheath
KW - Suction
UR - https://www.mendeley.com/catalogue/59943dd1-c9dc-3194-9c22-96d45021f21b/
U2 - 10.1002/bco2.70075
DO - 10.1002/bco2.70075
M3 - Article
C2 - 41069364
VL - 6
JO - BJUI Compass
JF - BJUI Compass
SN - 2688-4526
IS - 10
M1 - e70075
ER -
ID: 142724505