This paper reports on the integrated geochronological and geochemical methods used in studying the ore deposits and metalliferous sediments of the Yubileinoye field. This study gives the opportunity to carry out cross dating of hydrothermal deposits, including the ²³⁰Th/U dating of sulfides, the ²³⁰Th, ¹⁴C dating, and foraminiferal analysis of the sediments, and, on this basis, to reconstruct hydrothermal activity over time. It was established that the ores started forming about 100 000–123 000 years ago and were renewed 4–5 times with a frequency of 10–20 ka. As a result, the complex of pyrite-marcasite, chalcopyrite and sphalerite ores and the associated metal-bearing and ore-bearing sediments with consistent geochemical specialization were formed. The integrated geochronological and geochemical studies of the ores and sediments allow us to obtain detailed data on evolution of the hydrothermal ore-formation not only in the certain areas but also for the entire Mid-Atlantic Ridge.