Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
A two-step catalyst-free procedure for the construction of 3-perfluoroalkyl-2-(phosphoryl)methyl furans from commercially available 1-perfluoroalkyl 1,3-diketones is reported. Propargylic alcohols, prepared by direct alkynylation of the diketones, react with PCl3 via [2,3]-sigmatropic rearrangement – enolate cyclization sequence, leading to multifunctional furans. The reaction mechanism is supported by DFT study. In addition, the bioactivity modifying effect of phosphoryl group on 3-perfluoroalkyl furans is depicted. (Figure presented.).
Язык оригинала | английский |
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Страницы (с-по) | 3121-3125 |
Число страниц | 5 |
Журнал | Advanced Synthesis and Catalysis |
Том | 362 |
Номер выпуска | 15 |
DOI | |
Состояние | Опубликовано - 4 авг 2020 |
ID: 69889748