Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
In this work, a novel synthetic methodology for the one-pot preparation of isoxazoles directly from the reaction of calcium carbide with aldoximes is reported. Calcium carbide acts as a safe and inexpensive acetylene source and, in addition, as a source of the Ca(OH)2 base to enable the generation of nitrile oxide. Various 3-substituted isoxazoles were synthesized from the corresponding aldoximes in good yields (up to 95%) and a series of new deuterated 4,5-dideuteroisoxazoles were prepared.
Язык оригинала | английский |
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Страницы (с-по) | 226-231 |
Число страниц | 6 |
Журнал | Organic Chemistry Frontiers |
Том | 5 |
Номер выпуска | 2 |
DOI | |
Состояние | Опубликовано - 21 янв 2018 |
ID: 9326159