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Caffeine-DNA interaction and modification of radiation damage. / Paston, Sofia V.

BIT's 9th World Gene Convention - 2018: Conference Abstract book. 2018. стр. 081.

Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › тезисы в сборнике материалов конференции › научная

Harvard

Paston, SV 2018, Caffeine-DNA interaction and modification of radiation damage. в BIT's 9th World Gene Convention - 2018: Conference Abstract book. стр. 081, BIT's 9th World Gene Convention-2018, Singapore, 13/11/18.

APA

Paston, S. V. (2018). Caffeine-DNA interaction and modification of radiation damage. в BIT's 9th World Gene Convention - 2018: Conference Abstract book (стр. 081)

Vancouver

Paston SV. Caffeine-DNA interaction and modification of radiation damage. в BIT's 9th World Gene Convention - 2018: Conference Abstract book. 2018. стр. 081

Author

Paston, Sofia V. / Caffeine-DNA interaction and modification of radiation damage. BIT's 9th World Gene Convention - 2018: Conference Abstract book. 2018. стр. 081

BibTeX

@inbook{a2c7f8472ce0494d857c719ea400fa6a,
title = "Caffeine-DNA interaction and modification of radiation damage",
abstract = "We studied DNA interaction with caffeine and ions Mg2+ and Cu2+ in water solutions and dried films and influence of caffeine on DNA radiation damage. The main research methods were UV and IR-spectroscopy, UVCD, low gradient viscometry and atomic force microscopy. The results shows the caffeine-ions complexation, stronger with Cu2+ than with Mg2+. Addition of the third component to the DNA solution leads to the arising the DNA-caffeine-Me2+ complexes embracing the nitrogenous bases, which can be responsible for the prooxidant action. At the absence of divalent cations caffeine reveals the radioprotective action on DNA in solutions. In the presence of caffeine a decrease in the radiation effect on the DNA coil size in the solution, in the number of double-stranded breaks and damaged nitrogen bases, and in the degree of radiation-induced denaturation is observed. ",
keywords = "caffeine, ionizing radiation, DNA solutions and films, metal ions",
author = "Paston, {Sofia V.}",
year = "2018",
month = nov,
day = "13",
language = "English",
pages = "081",
booktitle = "BIT's 9th World Gene Convention - 2018",
note = "BIT's 9th World Gene Convention-2018 ; Conference date: 13-11-2018 Through 15-11-2018",

}

RIS

TY - CHAP

T1 - Caffeine-DNA interaction and modification of radiation damage

AU - Paston, Sofia V.

PY - 2018/11/13

Y1 - 2018/11/13

N2 - We studied DNA interaction with caffeine and ions Mg2+ and Cu2+ in water solutions and dried films and influence of caffeine on DNA radiation damage. The main research methods were UV and IR-spectroscopy, UVCD, low gradient viscometry and atomic force microscopy. The results shows the caffeine-ions complexation, stronger with Cu2+ than with Mg2+. Addition of the third component to the DNA solution leads to the arising the DNA-caffeine-Me2+ complexes embracing the nitrogenous bases, which can be responsible for the prooxidant action. At the absence of divalent cations caffeine reveals the radioprotective action on DNA in solutions. In the presence of caffeine a decrease in the radiation effect on the DNA coil size in the solution, in the number of double-stranded breaks and damaged nitrogen bases, and in the degree of radiation-induced denaturation is observed.

AB - We studied DNA interaction with caffeine and ions Mg2+ and Cu2+ in water solutions and dried films and influence of caffeine on DNA radiation damage. The main research methods were UV and IR-spectroscopy, UVCD, low gradient viscometry and atomic force microscopy. The results shows the caffeine-ions complexation, stronger with Cu2+ than with Mg2+. Addition of the third component to the DNA solution leads to the arising the DNA-caffeine-Me2+ complexes embracing the nitrogenous bases, which can be responsible for the prooxidant action. At the absence of divalent cations caffeine reveals the radioprotective action on DNA in solutions. In the presence of caffeine a decrease in the radiation effect on the DNA coil size in the solution, in the number of double-stranded breaks and damaged nitrogen bases, and in the degree of radiation-induced denaturation is observed.

KW - caffeine

KW - ionizing radiation

KW - DNA solutions and films

KW - metal ions

M3 - Conference abstracts

SP - 081

BT - BIT's 9th World Gene Convention - 2018

T2 - BIT's 9th World Gene Convention-2018

Y2 - 13 November 2018 through 15 November 2018

ER -

ID: 93796137