TY - JOUR

T1 - Block-copolymeric maltodextrin-based amphiphilic glycosilicones as surface-active systems

AU - Dobrynin, Mikhail V.

AU - Mongilev, Ilya V.

AU - Lezov, Alexey A.

AU - Perevyazko, Igor

AU - Tolstoy, Peter M.

AU - Anufrikov, Yurii A.

AU - Shasherina, Anna Yu

AU - Vlasov, Petr S.

AU - Kukushkin, Vadim Yu

AU - Islamova, Regina M.

N1 - Publisher Copyright: © 2022 The Royal Society of Chemistry.

PY - 2022/6/28

Y1 - 2022/6/28

N2 - Newly obtained amphiphilic glycosilicones are based on commercially available maltodextrins of various molecular weights (dextrose equivalent (DE) = 16.5-19.5 and 4-7) and hydride-terminated polydimethylsiloxane (Mw = 900). These carbohydrate polymers were synthesized via catalytic hydrosilylation employing Karstedt's catalyst, performed in benzene, between protected (by acetylation) and then modified (by allylation) maltodextrins with the hydride-terminated polydimethylsiloxane followed by deprotection. The block-copolymeric structure of the thus obtained glycosilicones was confirmed by 1H, 13C{1H}, and 29Si{1H} NMR spectroscopy. The carbohydrate polymers are soluble in water (<15 mg mL−1) and, in aqueous solutions, they form micelles, vesicles, and other aggregates with hydrodynamic radii spanning from 8 to 113 nm - as determined by dynamic light scattering, sedimentation experiments, and SEM. Titration calorimetry of glycosilicones based on maltodextrin demonstrates the critical micelle concentration of 13 mg mL−1 (ca. 10−3 mol L−1); these values are similar to those obtained for the commonly used alkylglucoside surfactants.

AB - Newly obtained amphiphilic glycosilicones are based on commercially available maltodextrins of various molecular weights (dextrose equivalent (DE) = 16.5-19.5 and 4-7) and hydride-terminated polydimethylsiloxane (Mw = 900). These carbohydrate polymers were synthesized via catalytic hydrosilylation employing Karstedt's catalyst, performed in benzene, between protected (by acetylation) and then modified (by allylation) maltodextrins with the hydride-terminated polydimethylsiloxane followed by deprotection. The block-copolymeric structure of the thus obtained glycosilicones was confirmed by 1H, 13C{1H}, and 29Si{1H} NMR spectroscopy. The carbohydrate polymers are soluble in water (<15 mg mL−1) and, in aqueous solutions, they form micelles, vesicles, and other aggregates with hydrodynamic radii spanning from 8 to 113 nm - as determined by dynamic light scattering, sedimentation experiments, and SEM. Titration calorimetry of glycosilicones based on maltodextrin demonstrates the critical micelle concentration of 13 mg mL−1 (ca. 10−3 mol L−1); these values are similar to those obtained for the commonly used alkylglucoside surfactants.

UR - http://www.scopus.com/inward/record.url?scp=85134937463&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/9f45a65f-37ea-3736-b3d6-cb90d5d4fb2d/

U2 - 10.1039/d2nj02285k

DO - 10.1039/d2nj02285k

M3 - Article

AN - SCOPUS:85134937463

VL - 46

SP - 14849

EP - 14858

JO - New Journal of Chemistry

JF - New Journal of Chemistry

SN - 1144-0546

IS - 31

ER -