Biocompatible Molecularly Imprinted Cryogel Matrices for Protein Recognition in Biological Samples

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Biocompatible Molecularly Imprinted Cryogel Matrices for Protein Recognition in Biological Samples. / Леонович, Мария Сергеевна ; Коржиков-Влах, Виктор Александрович ; Коржикова-Влах, Евгения Георгиевна ; Гурьянов, Иван Алексеевич; Бревнов, Олег Николаевич; Тенникова, Татьяна Борисовна.

в: Polymer Science. Series A, Том 66, № 1, 12.07.2024, стр. 21-31.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{bf750708ed8d4c56881460a5dc61faca,

title = "Biocompatible Molecularly Imprinted Cryogel Matrices for Protein Recognition in Biological Samples",

abstract = "Abstract: A series of molecularly imprinted and nonimprinted cryogels based on the copolymer of 2‑hydroxyethyl methacrylate and N,N '-methylene-bis(acrylamide) are synthesized at various ratios and contents of comonomers in the polymerization mixture. The resulting materials are characterized in terms of surface morphology, swelling ability, average pore size, porosity, and compression mechanical characteristics. In addition, a comparative assessment of the adsorption properties of the molecularly imprinted and nonimprinted cryogels with respect to a target protein (α-chymotrypsin) in the dynamic mode is performed, as well as the in vitro biocompatibility of the cryogels using two cell lines.",

author = "Леонович, {Мария Сергеевна} and Коржиков-Влах, {Виктор Александрович} and Коржикова-Влах, {Евгения Георгиевна} and Гурьянов, {Иван Алексеевич} and Бревнов, {Олег Николаевич} and Тенникова, {Татьяна Борисовна}",

year = "2024",

month = jul,

day = "12",

doi = "10.1134/s0965545x24600479",

language = "English",

volume = "66",

pages = "21--31",

journal = "Polymer Science - Series A",

issn = "0965-545X",

publisher = "МАИК {"}Наука/Интерпериодика{"}",

number = "1",

}

RIS

TY - JOUR

T1 - Biocompatible Molecularly Imprinted Cryogel Matrices for Protein Recognition in Biological Samples

AU - Леонович, Мария Сергеевна

AU - Коржиков-Влах, Виктор Александрович

AU - Коржикова-Влах, Евгения Георгиевна

AU - Гурьянов, Иван Алексеевич

AU - Бревнов, Олег Николаевич

AU - Тенникова, Татьяна Борисовна

PY - 2024/7/12

Y1 - 2024/7/12

N2 - Abstract: A series of molecularly imprinted and nonimprinted cryogels based on the copolymer of 2‑hydroxyethyl methacrylate and N,N '-methylene-bis(acrylamide) are synthesized at various ratios and contents of comonomers in the polymerization mixture. The resulting materials are characterized in terms of surface morphology, swelling ability, average pore size, porosity, and compression mechanical characteristics. In addition, a comparative assessment of the adsorption properties of the molecularly imprinted and nonimprinted cryogels with respect to a target protein (α-chymotrypsin) in the dynamic mode is performed, as well as the in vitro biocompatibility of the cryogels using two cell lines.

AB - Abstract: A series of molecularly imprinted and nonimprinted cryogels based on the copolymer of 2‑hydroxyethyl methacrylate and N,N '-methylene-bis(acrylamide) are synthesized at various ratios and contents of comonomers in the polymerization mixture. The resulting materials are characterized in terms of surface morphology, swelling ability, average pore size, porosity, and compression mechanical characteristics. In addition, a comparative assessment of the adsorption properties of the molecularly imprinted and nonimprinted cryogels with respect to a target protein (α-chymotrypsin) in the dynamic mode is performed, as well as the in vitro biocompatibility of the cryogels using two cell lines.

UR - https://www.mendeley.com/catalogue/ca43e57c-d3b4-31b0-a361-985cb9031e60/

U2 - 10.1134/s0965545x24600479

DO - 10.1134/s0965545x24600479

M3 - Article

VL - 66

SP - 21

EP - 31

JO - Polymer Science - Series A

JF - Polymer Science - Series A

SN - 0965-545X

IS - 1

ER -

ID: 121729117