Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Bacterial cellulose (Komagataeibacter rhaeticus) biocomposites and their cytocompatibility. / Petrova, Valentina A.; Khripunov, Albert K.; Golovkin, Alexey S.; Mishanin, Alexander I.; Gofman, Iosif V.; Romanov, Dmitry P.; Migunova, Alexandra V.; Arkharova, Natalia A.; Klechkovskaya, Vera V.; Skorik, Yury A.
в: Materials, Том 13, № 20, 4558, 02.10.2020, стр. 1-18.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Bacterial cellulose (Komagataeibacter rhaeticus) biocomposites and their cytocompatibility
AU - Petrova, Valentina A.
AU - Khripunov, Albert K.
AU - Golovkin, Alexey S.
AU - Mishanin, Alexander I.
AU - Gofman, Iosif V.
AU - Romanov, Dmitry P.
AU - Migunova, Alexandra V.
AU - Arkharova, Natalia A.
AU - Klechkovskaya, Vera V.
AU - Skorik, Yury A.
N1 - Funding Information: Acknowledgments: SEM studies were performed by Natalia A. Arkharova and Vera V. Klechkovskaya on the equipment of the Shared Research Center FSRC “Crystallography and Photonics” RAS (project RFMEFI62119X0035) supported by the Ministry of Science and Higher Education of the Russian Federation. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/10/2
Y1 - 2020/10/2
N2 - A series of novel polysaccharide-based biocomposites was obtained by impregnation of bacterial cellulose produced by Komagataeibacter rhaeticus (BC) with the solutions of negatively charged polysaccharides—hyaluronan (HA), sodium alginate (ALG), or κ-carrageenan (CAR)—and subsequently with positively charged chitosan (CS). The penetration of the polysaccharide solutions into the BC network and their interaction to form a polyelectrolyte complex changed the architecture of the BC network. The structure, morphology, and properties of the biocomposites depended on the type of impregnated anionic polysaccharides, and those polysaccharides in turn determined the nature of the interaction with CS. The porosity and swelling of the composites increased in the order: BC–ALG–CS > BC–HA–CS > BC–CAR–CS. The composites show higher biocompatibility with mesenchymal stem cells than the original BC sample, with the BC–ALG–CS composite showing the best characteristics.
AB - A series of novel polysaccharide-based biocomposites was obtained by impregnation of bacterial cellulose produced by Komagataeibacter rhaeticus (BC) with the solutions of negatively charged polysaccharides—hyaluronan (HA), sodium alginate (ALG), or κ-carrageenan (CAR)—and subsequently with positively charged chitosan (CS). The penetration of the polysaccharide solutions into the BC network and their interaction to form a polyelectrolyte complex changed the architecture of the BC network. The structure, morphology, and properties of the biocomposites depended on the type of impregnated anionic polysaccharides, and those polysaccharides in turn determined the nature of the interaction with CS. The porosity and swelling of the composites increased in the order: BC–ALG–CS > BC–HA–CS > BC–CAR–CS. The composites show higher biocompatibility with mesenchymal stem cells than the original BC sample, with the BC–ALG–CS composite showing the best characteristics.
KW - Alginate
KW - Bacterial cellulose
KW - Biocompatibility
KW - Biocomposites
KW - Carrageenan
KW - Chitosan
KW - Hyaluronan
KW - Komagataeibacter rhaeticus
KW - alginate
KW - chitosan
KW - COMPOSITES
KW - SPHEROID FORMATION
KW - IN-SITU
KW - biocomposites
KW - biocompatibility
KW - hyaluronan
KW - CORD BLOOD
KW - CHITOSAN
KW - HYDROXYAPATITE
KW - bacterial cellulose
KW - MESENCHYMAL STEM-CELLS
KW - carrageenan
KW - FABRICATION
KW - DIFFERENTIATION
KW - AGGREGATION
UR - http://www.scopus.com/inward/record.url?scp=85093967713&partnerID=8YFLogxK
U2 - 10.3390/ma13204558
DO - 10.3390/ma13204558
M3 - Article
AN - SCOPUS:85093967713
VL - 13
SP - 1
EP - 18
JO - Materials
JF - Materials
SN - 1996-1944
IS - 20
M1 - 4558
ER -
ID: 71874708